FNDC5: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of FNDC5. The page also collects GeneMedi's different modalities and formats products for FNDC5 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the FNDC5 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Transmembrane Protein.
This gene encodes a secreted protein that is released from muscle cells during exercise. The encoded protein may participate in the development of brown fat. Translation of the precursor protein initiates at a non-AUG start codon at a position that is conserved as an AUG start codon in other organisms. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2013]
Target ID | GM-MP0449 |
Target Name | FNDC5 |
Gene ID | 252995,384061,260327,710159,487302,101083019,538905,100146454 |
Gene Symbol and Synonyms | 1500001L03Rik,FNDC5,FRCP2,irisin,PeP,Pxp |
Uniprot Accession | Q8NAU1,Q8K3V5 |
Uniprot Entry Name | FNDC5_HUMAN,FNDC5_RAT |
Protein Sub-location | Transmembrane Protein |
Category | |
Disease | N/A |
Gene Ensembl | ENSG00000160097 |
Target Classification | N/A |
Pre-made anti-FNDC5 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-FNDC5 benchmark inhibitory monoclonal antibody(mab, blocking antibody inhibitor) is expressed by mammalian cell line as a benchmark antibody for cell culture, FACS, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-FNDC5 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-FNDC5 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | FACS/Biofunctional Antibody | Detail |
Multi-species FNDC5/ FRCP2/ irisin VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine FNDC5 VLP (virus-like particle) for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
FNDC5 VLP (virus-like particle) | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Products Developing |
Pre-made FNDC5 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLP000060 | human FNDC5 Lentivirus plasmid | NM_001171941 | Human | Lentivirus plasmid | Detail |
vGMLP000060 | human FNDC5 Lentivirus particle | NM_001171941 | Human | Lentivirus particle | Detail |
pGMAD000335 | mouse Fndc5 Adenovirus plasmid | NM_027402.4 | Mouse | Adenovirus plasmid | Detail |
pGMAAV000082 | mouse Fndc5 AAV plasmid | NM_027402.4 | Mouse | AAV plasmid | Detail |
pGMAAV000193 | house mouse Fndc5 AAV plasmid | NM_027402.4 | House Mouse | AAV plasmid | Detail |
pGMAAV000284 | house mouse Fndc5 AAV plasmid | NM_027402.4 | House Mouse | AAV plasmid | Detail |
vGMAD000335 | mouse Fndc5 Adenovirus particle | NM_027402.4 | Mouse | Adenovirus particle | Detail |
vGMAAV000082 | mouse Fndc5 AAV particle | NM_027402.4 | Mouse | AAV particle | Detail |
vGMAAV000193 | house mouse Fndc5 AAV particle | NM_027402.4 | House Mouse | AAV particle | Detail |
vGMAAV000284 | house mouse Fndc5 AAV particle | NM_027402.4 | House Mouse | AAV particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.