NDRG2: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD

It's the GeneMedi's summary page for Target/Biomarker Introduction of NDRG2. The page also collects GeneMedi's different modalities and formats products for NDRG2 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the NDRG2 target is also connected to human indications/diseases/conditions/MOA.

Target sublocation: Introcelluar Protein.

This gene is a member of the N-myc downregulated gene family which belongs to the alpha/beta hydrolase superfamily. The protein encoded by this gene is a cytoplasmic protein that may play a role in neurite outgrowth. This gene may be involved in glioblastoma carcinogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]

Target IDGM-IP1246
Target NameNDRG2
Gene ID57447,29811,171114,706990,609390,101083181,515063,100059072
Gene Symbol and SynonymsNdr2,NDRG2,SYLD
Uniprot AccessionQ9UN36,Q8VBU2,Q3ZBA8
Uniprot Entry NameNDRG2_HUMAN,NDRG2_RAT,NDRG2_BOVIN
Protein Sub-locationIntrocelluar Protein
Category
DiseaseCancer
Gene EnsemblENSG00000165795
Target ClassificationTumor-associated antigen (TAA)


Pre-made anti-NDRG2 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research

Pre-made anti-NDRG2 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-NDRG2 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.

Antibody NameSpeciesFormatClassified by tagDetail
Anti-NDRG2 monoclonal antibodyHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquinemabDetail



Recombinant multi-species NDRG2/ SYLD protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis

Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine NDRG2 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.

Products NameSpeciesExpression PlatformDetail
NDRG2 proteinHuman, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, EquineMammalian cellDetail



Pre-made NDRG2 viral vector in GM Promise-ORFTM

Cat No.Products nameNM IDSpeciesTypeDetail
vGMLV000612human NDRG2 Lentivirus particleNM_201535.1HumanLentivirus particleDetail
pGMLV000612human NDRG2 Lentivirus plasmidNM_201535.1HumanLentivirus plasmidDetail
vGMLP001970human NDRG2 Lentivirus particleNM_201537.1?HumanLentivirus particleDetail
pGMLP001970human NDRG2 Lentivirus plasmidNM_201537.1?HumanLentivirus plasmidDetail
pGMLV000561house mouse Ndrg2 Lentivirus plasmidNM_013864.2House MouseLentivirus plasmidDetail
pGMLV000599house mouse NDRG2 Lentivirus plasmidNM_001360264House MouseLentivirus plasmidDetail
pGMLPm001784mouse Ndrg2 Lentivirus plasmidNM_013864MouseLentivirus plasmidDetail
vGMLV000561house mouse Ndrg2 Lentivirus particleNM_013864.2House MouseLentivirus particleDetail
vGMLV000599house mouse NDRG2 Lentivirus particleNM_001360264House MouseLentivirus particleDetail
vGMLPm001784mouse Ndrg2 Lentivirus particleNM_013864MouseLentivirus particleDetail

About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI

If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.






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