HMOX1: Target/Biomarker Introduction, products summarized (antibody/ADC/bispecific/antigen/ORF vector/VLP) and disease/indication/condition/MOA for drug discovery and IVD
It's the GeneMedi's summary page for Target/Biomarker Introduction of HMOX1. The page also collects GeneMedi's different modalities and formats products for HMOX1 in therapeutics/drug discovery and IVD diagnostics, which is including antibody, ADC, bispecific, antigen, ORF vector, VLP, etc. With GeneMedi's target-insight database-GM ITD database, the HMOX1 target is also connected to human indications/diseases/conditions/MOA.
Target sublocation: Introcelluar Protein.
Heme oxygenase, an essential enzyme in heme catabolism, cleaves heme to form biliverdin, which is subsequently converted to bilirubin by biliverdin reductase, and carbon monoxide, a putative neurotransmitter. Heme oxygenase activity is induced by its substrate heme and by various nonheme substances. Heme oxygenase occurs as 2 isozymes, an inducible heme oxygenase-1 and a constitutive heme oxygenase-2. HMOX1 and HMOX2 belong to the heme oxygenase family. [provided by RefSeq, Jul 2008]
Target ID | GM-IP0044 |
Target Name | HMOX1 |
Gene ID | 3162,15368,24451,719266,442987,101092621,513221,100069058 |
Gene Symbol and Synonyms | bK286B10,D8Wsu38e,Hemox,Heox,HEOXG,Hmox,HMOX1,HMOX1D,HO-1,HO1,HSP32 |
Uniprot Accession | P09601,P06762,Q5E9F2 |
Uniprot Entry Name | HMOX1_HUMAN,HMOX1_RAT,HMOX1_BOVIN |
Protein Sub-location | Introcelluar Protein |
Category | Therapeutics Target |
Disease | Acute kidney failure, Renal tubulo-interstitial diseases |
Gene Ensembl | ENSG00000100292 |
Target Classification | N/A |
Pre-made anti-HMOX1 inhibitory monoclonal antibody(mab, blocking antibody inhibitor)-benchmark antibody for drug discovery and mechanism of action (MOA) research
Pre-made anti-HMOX1 monoclonal antibody(mab) is expressed by mammalian cell line as a benchmark antibody for cell culture, ELISA or other affinity binding assay or functional assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic). The anti-HMOX1 mab is expressed and produced by mammalian cell line as a benchmark reference therapeutic antibody for biological drug discovery items including cell culture, assay development, animal model development, PK/PD model development (Pharmacokinetics & Pharmacodynamic) and mechanism of action (MOA) research.
Antibody Name | Species | Format | Classified by tag | Detail |
Anti-HMOX1 monoclonal antibody | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | mab | Therapeutics Target antibody | Detail |
Recombinant multi-species HMOX1/ HMOX1D/ HO-1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis
Genemedi produces Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine HMOX1 protein for cell curture, in vitro study, in vivo study, benchmark, drug discovery & MOA research and positive control for the diagnosis.
Products Name | Species | Expression Platform | Detail |
HMOX1 protein | Human, Cynomolgus/ Rhesus macaque, Rat, Mouse, Feline, Canine, Bovine, Equine | Mammalian cell | Detail |
Pre-made HMOX1 viral vector in GM Promise-ORFTM
Cat No. | Products name | NM ID | Species | Type | Detail |
pGMLV000774 | human HMOX1 Lentivirus plasmid | NM_002133.2 | Human | Lentivirus plasmid | Detail |
pGMLP003511 | human HMOX1 Lentivirus plasmid | NM_002133 | Human | Lentivirus plasmid | Detail |
pGMLV000303 | human HMOX1 Lentivirus plasmid | NM_002133.2 | Human | Lentivirus plasmid | Detail |
vGMLP003511 | human HMOX1 Lentivirus particle | NM_002133 | Human | Lentivirus particle | Detail |
vGMLV000774 | human HMOX1 Lentivirus particle | NM_002133.2 | Human | Lentivirus particle | Detail |
pGMLV000302 | human HMOX1 Lentivirus plasmid | NM_002133.2 | Human | Lentivirus plasmid | Detail |
vGMLV000303 | human HMOX1 Lentivirus particle | NM_002133.2 | Human | Lentivirus particle | Detail |
vGMLV000302 | human HMOX1 Lentivirus particle | NM_002133.2 | Human | Lentivirus particle | Detail |
pGMLV000149 | mouse Hmox1 Lentivirus plasmid | NM_010442.2 | Mouse | Lentivirus plasmid | Detail |
pGMAD000236 | mouse Hmox1 Adenovirus plasmid | NM_010442.2 | Mouse | Adenovirus plasmid | Detail |
pGMAD000251 | rat Hmox1 Adenovirus plasmid | NM_012580.2 | Rat | Adenovirus plasmid | Detail |
pGMAAV000324 | Norway rat Hmox1 AAV plasmid | NM_012580 | Norway Rat | AAV plasmid | Detail |
vGMLV000149 | mouse Hmox1 Lentivirus particle | NM_010442.2 | Mouse | Lentivirus particle | Detail |
vGMAD000236 | mouse Hmox1 Adenovirus particle | NM_010442.2 | Mouse | Adenovirus particle | Detail |
vGMAD000251 | rat Hmox1 Adenovirus particle | NM_012580.2 | Rat | Adenovirus particle | Detail |
vGMAAV000324 | Norway rat Hmox1 AAV particle | NM_012580 | Norway Rat | AAV particle | Detail |
About Promise-ORFTM:
Discover the largest collection of ORF/cDNA expression clones from different species, including human, mouse, rat, and more with GeneMedi's Promise-ORFTM. Our collection of ORFs expression clones come in verified mammalian or viral vectors lentivirus, AAV, and adenovirus) and our Promise-ORFTM viral-ready expression vectors make it easy for you to improve viral vector packaging efficiency or directly transfect mammalian cells, resulting in stronger and easier expression detection. Click to search your GOI
If you want to obtain higher quantities of plasmids (mg), please visit GM TransExcellent Plasmid DNA Rapid Preparation Service.