soluble fragment of triggering receptor expressed on myeloid cells 2 (sTREM2) antibody and antigen (Recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-sTREM2-Ag01	Recombinant human TREM2/sTREM2 Protein	3090
GMP-h-sTREM2-Ab01	Anti-human TREM2/sTREM2 mouse monoclonal antibody (mAb)	1953
GMP-h-sTREM2-Ab02	Anti-human TREM2/sTREM2 mouse monoclonal antibody (mAb)	1953
GMP-h-sTREM2-Ab03	Anti-human TREM2/sTREM2 human monoclonal antibody (mAb)	1953
GMP-h-sTREM2-Ab04	Anti-human TREM2/sTREM2 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-h-sTREM2-Ag01
Product Name	Recombinant human TREM2/sTREM2 Protein
Target/Biomarker	soluble fragment of triggering receptor expressed on myeloid cells 2 (sTREM2)
Alias of Target/Biomarker	PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	soluble fragment of triggering receptor expressed on myeloid cells 2 (sTREM2) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sTREM2 level test of Neurodegenerative diseases (Alzheimer Disease (AD)) and related syndrome evaluation.
Tag	His
Products description	Recombinant human TREM2/sTREM2 Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-sTREM2-Ab01, GMP-h-sTREM2-Ab02
Product Name	Anti-human TREM2/sTREM2 mouse monoclonal antibody (mAb)
Target/Biomarker	soluble fragment of triggering receptor expressed on myeloid cells 2 (sTREM2)
Alias of Target/Biomarker	PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	soluble fragment of triggering receptor expressed on myeloid cells 2 (sTREM2) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sTREM2 level test of Neurodegenerative diseases (Alzheimer Disease (AD)) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human TREM2/sTREM2 mouse monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-sTREM2-Ab03, GMP-h-sTREM2-Ab04
Product Name	Anti-human TREM2/sTREM2 human monoclonal antibody (mAb)
Target/Biomarker	soluble fragment of triggering receptor expressed on myeloid cells 2 (sTREM2)
Alias of Target/Biomarker	PLOSL2, TREM-2, Trem2a, Trem2b, Trem2c
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	soluble fragment of triggering receptor expressed on myeloid cells 2 (sTREM2) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sTREM2 level test of Neurodegenerative diseases (Alzheimer Disease (AD)) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human TREM2/sTREM2 human monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

TREM2 is a microglial transmembrane protein that is proteolytically processed to release a soluble fragment (sTREM2). Meta-analysis of available data finds sTREM2 levels are somewhat higher in people with AD than in controls (effect size = 1.314, p <0.0001).

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