soluble vascular endothelial growth factor receptor-1 (sFlt-1) antibody and antigen (Recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-sFlt-1-Ag01	Recombinant human FLT1/ FSD2/sFlt-1/FLT/ SPRYD1/FRT Protein	3090
GMP-h-sFlt-1-Ab01	Anti-human FLT1/ FSD2/sFlt-1/FLT/ SPRYD1/FRT mouse monoclonal antibody (mAb)	1953
GMP-h-sFlt-1-Ab02	Anti-human FLT1/ FSD2/sFlt-1/FLT/ SPRYD1/FRT mouse monoclonal antibody (mAb)	1953
GMP-h-sFlt-1-Ab03	Anti-human FLT1/ FSD2/sFlt-1/FLT/ SPRYD1/FRT human monoclonal antibody (mAb)	1953
GMP-h-sFlt-1-Ab04	Anti-human FLT1/ FSD2/sFlt-1/FLT/ SPRYD1/FRT human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-h-sFlt-1-Ag01
Product Name	Recombinant human FLT1/ FSD2/sFlt-1/FLT/ SPRYD1/FRT Protein
Target/Biomarker	soluble vascular endothelial growth factor receptor-1 (sFlt-1)
Alias of Target/Biomarker	FLT, FLT-1, VEGFR-1, VEGFR1, SPRYD1
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	soluble vascular endothelial growth factor receptor-1 (sFlt-1) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sFlt-1 level test of Cancer (ascular diseases and cancer) and related syndrome evaluation.
Tag	His
Products description	Recombinant human FLT1/ FSD2/sFlt-1/FLT/ SPRYD1/FRT Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-sFlt-1-Ab01, GMP-h-sFlt-1-Ab02
Product Name	Anti-human FLT1/ FSD2/sFlt-1/FLT/ SPRYD1/FRT mouse monoclonal antibody (mAb)
Target/Biomarker	soluble vascular endothelial growth factor receptor-1 (sFlt-1)
Alias of Target/Biomarker	FLT, FLT-1, VEGFR-1, VEGFR1, SPRYD1
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	soluble vascular endothelial growth factor receptor-1 (sFlt-1) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sFlt-1 level test of Cancer (ascular diseases and cancer) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human FLT1/ FSD2/sFlt-1/FLT/ SPRYD1/FRT mouse monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-sFlt-1-Ab03, GMP-h-sFlt-1-Ab04
Product Name	Anti-human FLT1/ FSD2/sFlt-1/FLT/ SPRYD1/FRT human monoclonal antibody (mAb)
Target/Biomarker	soluble vascular endothelial growth factor receptor-1 (sFlt-1)
Alias of Target/Biomarker	FLT, FLT-1, VEGFR-1, VEGFR1, SPRYD1
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	soluble vascular endothelial growth factor receptor-1 (sFlt-1) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in sFlt-1 level test of Cancer (ascular diseases and cancer) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human FLT1/ FSD2/sFlt-1/FLT/ SPRYD1/FRT human monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Formation of new capillary blood vessels from existing microvessels is called Angiogenesis, which plays a fundamental role in many physiological and pathological processes such as embryo genesis, wound healing and cancer. Angiogenic processes are controlled by a multitude of positive and negative regulators. Vascular endothelial growth factor (VEGF) strongly promotes angiogenesis. VEGF exerts multiple reactions by activating cell membrane receptors with tyrosine kinase activity, such as VEGFR-1 (Flt-1), VEGFR-2 (KDR/Flk-1) and VEGFR-3 (Flt-4) (4). The soluble form of the FLT-1 receptor, sFLT-1, is one of the efficient inhibitors of angiogenesis (10,12). The sFLT-1 inhibits VEGF-driven migration of cancer cells.  VEGF or sFLT-1 genes or their products have been involved in the therapy of vascular diseases and cancer.

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