collagen type IV (cIV) antibody and antigen (Recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-cIV-Ag01	Recombinant human COL4A1/ COL4A2/cIV Protein	3090
GMP-h-cIV-Ab01	Anti-human COL4A1/ COL4A2/cIV mouse monoclonal antibody (mAb)	1953
GMP-h-cIV-Ab02	Anti-human COL4A1/ COL4A2/cIV mouse monoclonal antibody (mAb)	1953
GMP-h-cIV-Ab03	Anti-human COL4A1/ COL4A2/cIV human monoclonal antibody (mAb)	1953
GMP-h-cIV-Ab04	Anti-human COL4A1/ COL4A2/cIV human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-h-cIV-Ag01
Product Name	Recombinant human COL4A1/ COL4A2/cIV Protein
Target/Biomarker	collagen type IV (cIV)
Alias of Target/Biomarker	BSVD, BSVD1, COL4A1s, PADMAL, RATOR, BSVD2, ICH, POREN2
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	collagen type IV (cIV) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cIV level test of Liver diseases (Goodpasture syndrome, Alport syndrome,  glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps.  porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury.) and related syndrome evaluation.
Tag	His
Products description	Recombinant human COL4A1/ COL4A2/cIV Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-cIV-Ab01, GMP-h-cIV-Ab02
Product Name	Anti-human COL4A1/ COL4A2/cIV mouse monoclonal antibody (mAb)
Target/Biomarker	collagen type IV (cIV)
Alias of Target/Biomarker	BSVD, BSVD1, COL4A1s, PADMAL, RATOR, BSVD2, ICH, POREN2
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	collagen type IV (cIV) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cIV level test of Liver diseases (Goodpasture syndrome, Alport syndrome,  glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps.  porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury.) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human COL4A1/ COL4A2/cIV mouse monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-cIV-Ab03, GMP-h-cIV-Ab04
Product Name	Anti-human COL4A1/ COL4A2/cIV human monoclonal antibody (mAb)
Target/Biomarker	collagen type IV (cIV)
Alias of Target/Biomarker	BSVD, BSVD1, COL4A1s, PADMAL, RATOR, BSVD2, ICH, POREN2
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	collagen type IV (cIV) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in cIV level test of Liver diseases (Goodpasture syndrome, Alport syndrome,  glomerular basement membrane, Liver fibrosis and cirrhosis, alcoholic liver disease, hepatitis C and fall following successful therapy. autosomal dominant hereditary angiopathy, nephropathy, aneurysms, and muscle cramps.  porencephaly, schizencephaly, congenital cataract, coronary artery disease, diabetic nephropathy and renal injury.) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human COL4A1/ COL4A2/cIV human monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

The serum type IV collagen test is now used as a diagnostic aid for the detection of liver fibrosis and cirrhosis. Recently, a platelet count has been reported to be a useful marker for assessing the fibrotic stage in chronic hepatitis C.

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