Thymidine Kinase 1 (TK1) antibody and antigen (Recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-TK1-Ag01	Recombinant human TK1 Protein	3090
GMP-h-TK1-Ab01	Anti-human TK1 mouse monoclonal antibody (mAb)	1953
GMP-h-TK1-Ab02	Anti-human TK1 mouse monoclonal antibody (mAb)	1953
GMP-h-TK1-Ab03	Anti-human TK1 human monoclonal antibody (mAb)	1953
GMP-h-TK1-Ab04	Anti-human TK1 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-h-TK1-Ag01
Product Name	Recombinant human TK1 Protein
Target/Biomarker	Thymidine Kinase 1 (TK1)
Alias of Target/Biomarker	TK2
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	Thymidine Kinase 1 (TK1) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TK1 level test of Cancer (hematological malignancies) and related syndrome evaluation.
Tag	His
Products description	Recombinant human TK1 Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-TK1-Ab01, GMP-h-TK1-Ab02
Product Name	Anti-human TK1 mouse monoclonal antibody (mAb)
Target/Biomarker	Thymidine Kinase 1 (TK1)
Alias of Target/Biomarker	TK2
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Thymidine Kinase 1 (TK1) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TK1 level test of Cancer (hematological malignancies) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human TK1 mouse monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-TK1-Ab03, GMP-h-TK1-Ab04
Product Name	Anti-human TK1 human monoclonal antibody (mAb)
Target/Biomarker	Thymidine Kinase 1 (TK1)
Alias of Target/Biomarker	TK2
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Thymidine Kinase 1 (TK1) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in TK1 level test of Cancer (hematological malignancies) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human TK1 human monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Thymidine kinase 1 (TK1) is a key enzyme in DNA precursor synthesis. It is upregulated during the S phase of the cell cycle and its presence in cells is an indicator of active cell proliferation. TK1 has been shown as a clinically valuable biomarker for the management of hematological malignancies. Elevated serum thymidine kinase 1 is associated with pre/early cancerous progression. High levels of HER2 and Ki-67 or TK1 expression correlate with the increase of tumor grades and tumor recurrence in meningiomas.

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