amino-terminal propeptide (PINP) antibody and antigen (Recombinant protein)

 Download 

Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-PINP-Ag01	Recombinant human COL1A1/PINP Protein	3090
GMP-h-PINP-Ab01	Anti-human COL1A1/PINP mouse monoclonal antibody (mAb)	1953
GMP-h-PINP-Ab02	Anti-human COL1A1/PINP mouse monoclonal antibody (mAb)	1953
GMP-h-PINP-Ab03	Anti-human COL1A1/PINP human monoclonal antibody (mAb)	1953
GMP-h-PINP-Ab04	Anti-human COL1A1/PINP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-h-PINP-Ag01
Product Name	Recombinant human COL1A1/PINP Protein
Target/Biomarker	amino-terminal propeptide (PINP)
Alias of Target/Biomarker	CAFYD, EDSARTH1, EDSC, OI1, OI2, OI3, OI4
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	amino-terminal propeptide (PINP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PINP level test of Metabolic diseases (osteoporosis therapy) and related syndrome evaluation.
Tag	His
Products description	Recombinant human COL1A1/PINP Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-PINP-Ab01, GMP-h-PINP-Ab02
Product Name	Anti-human COL1A1/PINP mouse monoclonal antibody (mAb)
Target/Biomarker	amino-terminal propeptide (PINP)
Alias of Target/Biomarker	CAFYD, EDSARTH1, EDSC, OI1, OI2, OI3, OI4
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	amino-terminal propeptide (PINP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PINP level test of Metabolic diseases (osteoporosis therapy) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human COL1A1/PINP mouse monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-PINP-Ab03, GMP-h-PINP-Ab04
Product Name	Anti-human COL1A1/PINP human monoclonal antibody (mAb)
Target/Biomarker	amino-terminal propeptide (PINP)
Alias of Target/Biomarker	CAFYD, EDSARTH1, EDSC, OI1, OI2, OI3, OI4
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	amino-terminal propeptide (PINP) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PINP level test of Metabolic diseases (osteoporosis therapy) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human COL1A1/PINP human monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Procollagen type I propeptides are derived from collagen type I, which is the most common collagen type found in mineralized bone. In bone, collagen is synthesized by osteoblasts in the form of procollagen. This precursor contains a short signal sequence and terminal extension peptides: amino-terminal propeptide (PINP) and carboxy-terminal propeptide. These propeptide extensions are removed by specific proteinases before the collagen molecules form. Both propeptides can be found in the circulation and their concentration reflects the synthesis rate of collagen type I. Although collagen type I propeptides may also arise from other tissues (such as the skin, vessels, fibrocartilage, and tendons), most nonskeletal tissues exhibit a slower turnover than bone, and contribute very little to the circulating pool of PINP. PINP is considered the most sensitive marker of bone formation and it is particularly useful for monitoring bone formation therapies and antiresorptive therapies; it is recommended that the test be performed at baseline before starting osteoporosis therapy and performed again 3 to 6 months later.

About GDU