Interferon gamma (IFNγ) antibody and antigen (Recombinant protein)

Diagnostic Interferon gamma (IFNγ) antibodies (anti-Interferon gamma, anti-IFNγ) and antigens (recombinant Interferon gamma (IFNγ) protein) for Inflammation/autoimmune/inflammatory disease IFNγ detection in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT.

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Product information

Catalog No. Description US $ Price (per mg)
GMP-h-IFNγ-Ag01 Recombinant human IFNG/IFNγ Protein 3090
GMP-h-IFNγ-Ab01 Anti-human IFNG/IFNγ mouse monoclonal antibody (mAb) 1953
GMP-h-IFNγ-Ab02 Anti-human IFNG/IFNγ mouse monoclonal antibody (mAb) 1953
GMP-h-IFNγ-Ab03 Anti-human IFNG/IFNγ human monoclonal antibody (mAb) 1953
GMP-h-IFNγ-Ab04 Anti-human IFNG/IFNγ human monoclonal antibody (mAb) 1953

Size: 1mg | 10mg | 100mg



Product Description

Cat No. of Products GMP-h-IFNγ-Ag01
Product Name Recombinant human IFNG/IFNγ Protein
Target/Biomarker Interferon gamma (IFNγ)
Alias of Target/Biomarker IFG, IFI, IMD69
Expression platform mammalian
Isotypes Recombinant Antigen
Bioactivity validation Interferon gamma (IFNγ) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in IFNγ level test of Inflammation/autoimmune/inflammatory disease (inflamation, autoimmune disease) and related syndrome evaluation.
Tag His
Products description Recombinant human IFNG/IFNγ Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-h-IFNγ-Ab01, GMP-h-IFNγ-Ab02
Product Name Anti-human IFNG/IFNγ mouse monoclonal antibody (mAb)
Target/Biomarker Interferon gamma (IFNγ)
Alias of Target/Biomarker IFG, IFI, IMD69
Expression platform CHO
Isotypes Mouse IgG
Bioactivity validation Interferon gamma (IFNγ) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in IFNγ level test of Inflammation/autoimmune/inflammatory disease (inflamation, autoimmune disease) and related syndrome evaluation.
Tag mFc
Products description Anti-human IFNG/IFNγ mouse monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products GMP-h-IFNγ-Ab03, GMP-h-IFNγ-Ab04
Product Name Anti-human IFNG/IFNγ human monoclonal antibody (mAb)
Target/Biomarker Interferon gamma (IFNγ)
Alias of Target/Biomarker IFG, IFI, IMD69
Expression platform CHO
Isotypes Human lgG1
Bioactivity validation Interferon gamma (IFNγ) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in IFNγ level test of Inflammation/autoimmune/inflammatory disease (inflamation, autoimmune disease) and related syndrome evaluation.
Tag hFc
Products description Anti-human IFNG/IFNγ human monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity Purity: ≥95% (SDS-PAGE)
Application ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference




    Validation Data


    GeneMedi's IFNγ antibodies demonstrate superior performance in immunoassay


    GMP-h-a-IFN Validation

    GeneMedi’s GMP-h-IFNγ-Ab03 and GMP-h-IFNγ-Ab04 antibodies demonstrate superior performance in sandwich ELISA assays compared to other commercial products. Their exceptional sensitivity is reflected in significantly lower EC50 values, indicating enhanced binding affinity and detection capability. These properties make them an excellent choice for applications requiring high precision and reliability in quantitative analysis, offering researchers greater confidence in their assay results.

    Figure 1. GeneMedi’s GMP-h-IFNγ-Ab03 and GMP-h-IFNγ-Ab04 antibodies demonstrate superior performance in sandwich ELISA assays compared to other commercial products.

    A.The binding curves of different GMP-h-IFNγ-Ab03 coating concentrations and GMP-h-IFNγ-Ab04 biotin detecting concentrations.
    B-D. Sandwich ELISA assay using 0.5ug/ml (B), 1ug/ml (C), and 2ug/ml (D) capture antibody (GMP-h-IFNγ-Ab03) with different concentrations of the detection antibody (GMP-h-IFNγ-Ab04) biotin. The unique commercial antibody pair is used for Head-to-head comparation in this study.
    E.The EC50 results of different GMP-h-IFNγ-Ab03 coating concentrations and GMP-h-IFNγ-Ab04 biotin detecting concentrations.

    Click to get more Data / Case study about the product.



    Target/Biomarker information

    Interferon gamma  (IFNγ) is a dimerized soluble cytokine that is the only member of the type II class of interferons.[1] The existence of this interferon, which early in its history was known as immune interferon, was described by E. F. Wheelock as a product of human leukocytes stimulated with phytohemagglutinin, and by others as a product of antigen-stimulated lymphocytes.[2] It was also shown to be produced in lymphocytes.[3] or tuberculin-sensitized mouse peritoneal lymphocytes[4] challenged with PPD; the resulting supernatants were shown to inhibit growth of vesicular stomatitis virus. Those reports also contained the basic observation underlying the now widely employed interferon gamma release assay used to test for tuberculosis. In humans, the IFNγ protein is encoded by the IFNG gene.



    About GDU


    GDU

    GDU helps global diagnostic partners in high quality of raw material discovery, development, and application. GDU believes in Protein&antibody Innovation for more reliable diagnostic solutions.

    Comments


    Charles Wilson 2024-03-09 02:56:16
    The IFN antibody shows very good stability and high quality data that make it suitable for Chemiluminescent Immunoassay (CLIA). It guarantees accurate detection of the diseases.

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