Heparin-binding protein (HBP) antibody and antigen (Recombinant protein)

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Product information

Size： 1mg | 10mg | 100mg

Catalog No.	Description	US $ Price (per mg)	First Order Discount	First Order Discount Price
GMP-h-HBP-Ag01	Recombinant human AZU1/ALB Protein	3090
GMP-h-HBP-Ab01	Anti-human AZU1/HBP mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-h-HBP-Ab02	Anti-human AZU1/HBP mouse monoclonal antibody (mAb)	1953	20%	1562.4
GMP-h-HBP-Ab03	Anti-human AZU1/HBP human monoclonal antibody (mAb)	1953	20%	1562.4
GMP-h-HBP-Ab04	Anti-human AZU1/HBP human monoclonal antibody (mAb)	1953	20%	1562.4

Shipping Costs: $360–$760
Antibodies: $360 Antigens: $760 (Elevated cost due to antigen heterogeneity, post-translational modifications, structural complexity, and specialized handling.)

Product Description

Cat No. of Products	GMP-h-HBP-Ag01
Product Name	Recombinant human AZU1/ALB Protein
Target/Biomarker	Heparin-binding protein (ALB)
Alias of Target/Biomarker	AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC, hHBP
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	Heparin-binding protein (ALB) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ALB level test of Inflammation/autoimmune/inflammatory disease (inflammation/autoimmune/ inflammatory disease) and related syndrome evaluation.
Tag	His
Products description	Recombinant human AZU1/ALB Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-HBP-Ab01, GMP-h-HBP-Ab02
Product Name	Anti-human AZU1/HBP mouse monoclonal antibody (mAb)
Target/Biomarker	Heparin-binding protein (ALB)
Alias of Target/Biomarker	AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC, hHBP
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Heparin-binding protein (ALB) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ALB level test of Inflammation/autoimmune/inflammatory disease (inflammation/autoimmune/ inflammatory disease) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human AZU1/HBP mouse monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-HBP-Ab03, GMP-h-HBP-Ab04
Product Name	Anti-human AZU1/HBP human monoclonal antibody (mAb)
Target/Biomarker	Heparin-binding protein (ALB)
Alias of Target/Biomarker	AZAMP, AZU, CAP37, HBP, HUMAZUR, NAZC, hHBP
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Heparin-binding protein (ALB) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in ALB level test of Inflammation/autoimmune/inflammatory disease (inflammation/autoimmune/ inflammatory disease) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human AZU1/HBP human monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

The incidence of sepsis increases with ageing, rise in cancer incidence and popularity of invasive medical operations.1 2 Rapid detection and optimised treatment are the keys to successful treatment of sepsis.3 To facilitate earlier recognition and more timely management of patients with sepsis or those at risk of developing the condition, the European Society of Intensive Care Medicine and Society of Critical Care Medicine published new diagnostic criteria for sepsis and septic shock.4 Nevertheless, due to time delay, low sensitivity and lack of specificity,5 the existing diagnosis indicators such as microbial culture, complete blood count, and levels of procalcitonin (PCT) and C reactive protein (CRP) are inadequate for timely clinical diagnosis of sepsis and septic shock. Heparin-binding protein (HBP) is precomposed and mainly exists in the azurophilic granules (almost 74% in content) and secretory vesicles (almost 18% in content) of neutrophils. Azurophilic granules show low tendency to be released from cells, and they are only released when neutrophils infiltrate tissues.6 The release of easily mobilised HBP from secretory vesicles has important functions during early events in inflammatory processes. HBP works by activating various cell types.7 Previous studies have shown that the plasma HBP level is significantly elevated in sepsis combined with organ dysfunction, which is the best probe for the progression of sepsis.3 8 Given the capacity of HBP to identify infection and vascular leakage in patients, it is also an interesting candidate marker to monitor patients with sepsis and septic shock.

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