Growth differentiation factor-15 (GDF-15) antibody and antigen (Recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-GDF-15-Ag01	Recombinant human GDF15/GDF-15/MIC1/PDF Protein	3090
GMP-h-GDF-15-Ab01	Anti-human GDF15/GDF-15/MIC1/PDF mouse monoclonal antibody (mAb)	1953
GMP-h-GDF-15-Ab02	Anti-human GDF15/GDF-15/MIC1/PDF mouse monoclonal antibody (mAb)	1953
GMP-h-GDF-15-Ab03	Anti-human GDF15/GDF-15/MIC1/PDF human monoclonal antibody (mAb)	1953
GMP-h-GDF-15-Ab04	Anti-human GDF15/GDF-15/MIC1/PDF human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-h-GDF-15-Ag01
Product Name	Recombinant human GDF15/GDF-15/MIC1/PDF Protein
Target/Biomarker	Growth differentiation factor-15 (GDF-15)
Alias of Target/Biomarker	GDF-15, HG, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	Growth differentiation factor-15 (GDF-15) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GDF-15 level test of Cardiovascular disease (pressure overload, myocardial infarction, heart failure, and atherosclerosis) and related syndrome evaluation.
Tag	His
Products description	Recombinant human GDF15/GDF-15/MIC1/PDF Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-GDF-15-Ab01, GMP-h-GDF-15-Ab02
Product Name	Anti-human GDF15/GDF-15/MIC1/PDF mouse monoclonal antibody (mAb)
Target/Biomarker	Growth differentiation factor-15 (GDF-15)
Alias of Target/Biomarker	GDF-15, HG, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Growth differentiation factor-15 (GDF-15) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GDF-15 level test of Cardiovascular disease (pressure overload, myocardial infarction, heart failure, and atherosclerosis) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human GDF15/GDF-15/MIC1/PDF mouse monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-GDF-15-Ab03, GMP-h-GDF-15-Ab04
Product Name	Anti-human GDF15/GDF-15/MIC1/PDF human monoclonal antibody (mAb)
Target/Biomarker	Growth differentiation factor-15 (GDF-15)
Alias of Target/Biomarker	GDF-15, HG, MIC-1, MIC1, NAG-1, PDF, PLAB, PTGFB
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Growth differentiation factor-15 (GDF-15) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in GDF-15 level test of Cardiovascular disease (pressure overload, myocardial infarction, heart failure, and atherosclerosis) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human GDF15/GDF-15/MIC1/PDF human monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Growth and differentiation factor 15 (GDF-15), previously known as macrophage inhibitory cytokine 1 (MIC-1), is a divergent transforming growth factor β (TGF-β) family member historically associated with cancer cachexia, cardiovascular disease, and a host of other diseases with inflammatory etiologies. GDF-15 is expressed in most tissues only at very low levels, the only human organ that expresses high levels of GDF-15 in healthy conditions is the placenta. However, GDF-15 could be markedly increased in the case of cardiovascular injury, such as pressure overload, myocardial infarction, heart failure, and atherosclerosis.

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