D dimer (D-Dimer) antibody and antigen (Recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-D-Dimer-Ag01	Recombinant human D-Dimer Protein	3090
GMP-h-D-Dimer-Ab01	Anti-human D-Dimer mouse monoclonal antibody (mAb)	1953
GMP-h-D-Dimer-Ab02	Anti-human D-Dimer mouse monoclonal antibody (mAb)	1953
GMP-h-D-Dimer-Ab03	Anti-human D-Dimer human monoclonal antibody (mAb)	1953
GMP-h-D-Dimer-Ab04	Anti-human D-Dimer human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-h-D-Dimer-Ag01
Product Name	Recombinant human D-Dimer Protein
Target/Biomarker	D dimer (D-Dimer)
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	D dimer (D-Dimer) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in D-Dimer level test of Cardiovascular disease (Deep vein thrombosis (DVT)) and related syndrome evaluation.
Tag	His
Products description	Recombinant human D-Dimer Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-D-Dimer-Ab01, GMP-h-D-Dimer-Ab02
Product Name	Anti-human D-Dimer mouse monoclonal antibody (mAb)
Target/Biomarker	D dimer (D-Dimer)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	D dimer (D-Dimer) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in D-Dimer level test of Cardiovascular disease (Deep vein thrombosis (DVT)) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human D-Dimer mouse monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-D-Dimer-Ab03, GMP-h-D-Dimer-Ab04
Product Name	Anti-human D-Dimer human monoclonal antibody (mAb)
Target/Biomarker	D dimer (D-Dimer)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	D dimer (D-Dimer) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in D-Dimer level test of Cardiovascular disease (Deep vein thrombosis (DVT)) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human D-Dimer human monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

D-dimer (or D dimer) is a fibrin degradation product (or FDP), a small protein fragment present in the blood after a blood clot is degraded by fibrinolysis. It is so named because it contains two D fragments of the fibrin protein joined by a cross-link.[1] D-dimer concentration may be determined by a blood test to help diagnose thrombosis.[2] Since its introduction in the 1990s, it has become an important test performed in people with suspected thrombotic disorders, such as venous thromboembolism.[2][3] While a negative result practically rules out thrombosis, a positive result can indicate thrombosis, but does not exclude other potential causes.[3] Its main use, therefore, is to exclude thromboembolic disease where the probability is low.[1][2] D-dimer levels are used as a predictive biomarker for the blood disorder, disseminated intravascular coagulation and in the coagulation disorders associated with COVID-19 infection.[1][3] A four-fold increase in the protein is an indicator of poor prognosis in people hospitalized with COVID-19.

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