creatine kinase myocardial band (CKMB) antibody and antigen (Recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-CKMB-Ag01	Recombinant human CKM/CKMB/CKMM Protein	3090
GMP-h-CKMB-Ab01	Anti-human CKM/CKMB/CKMM mouse monoclonal antibody (mAb)	1953
GMP-h-CKMB-Ab02	Anti-human CKM/CKMB/CKMM mouse monoclonal antibody (mAb)	1953
GMP-h-CKMB-Ab03	Anti-human CKM/CKMB/CKMM human monoclonal antibody (mAb)	1953
GMP-h-CKMB-Ab04	Anti-human CKM/CKMB/CKMM human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-h-CKMB-Ag01
Product Name	Recombinant human CKM/CKMB/CKMM Protein
Target/Biomarker	creatine kinase myocardial band (CKMB)
Alias of Target/Biomarker	CKMM, CPK-M, M-CK
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	creatine kinase myocardial band (CKMB) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CKMB level test of Cardiovascular disease (acute myocardial infarction) and related syndrome evaluation.
Tag	His
Products description	Recombinant human CKM/CKMB/CKMM Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-CKMB-Ab01, GMP-h-CKMB-Ab02
Product Name	Anti-human CKM/CKMB/CKMM mouse monoclonal antibody (mAb)
Target/Biomarker	creatine kinase myocardial band (CKMB)
Alias of Target/Biomarker	CKMM, CPK-M, M-CK
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	creatine kinase myocardial band (CKMB) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CKMB level test of Cardiovascular disease (acute myocardial infarction) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human CKM/CKMB/CKMM mouse monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-CKMB-Ab03, GMP-h-CKMB-Ab04
Product Name	Anti-human CKM/CKMB/CKMM human monoclonal antibody (mAb)
Target/Biomarker	creatine kinase myocardial band (CKMB)
Alias of Target/Biomarker	CKMM, CPK-M, M-CK
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	creatine kinase myocardial band (CKMB) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CKMB level test of Cardiovascular disease (acute myocardial infarction) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human CKM/CKMB/CKMM human monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

is a cardiac marker used to assist diagnoses of an acute myocardial infarction. It measures the blood level of CK-MB (creatine kinase myocardial band), the bound combination of two variants (isoenzymes CKM and CKB) of the enzyme phosphocreatine kinase.recently, there have been improvements to the test that involve measuring the ratio of the CK-MB1 and CK-MB2 isoformsThe newer test detects different isoforms of the B subunit specific to the myocardium whereas the older test detected the presence of cardiac-related isoenzyme dimers. Many cases of CK-MB levels exceeding the blood level of total CK have been reported, especially in newborns with cardiac malformations, especially ventricular septal defects. This reversal of ratios is in favor of pulmonary emboli or vasculitis. An autoimmune reaction creating a complex molecule of CK and IgG should be taken into consideration.

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