Beta-2 microglobulin (B2M) antibody and antigen (Recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-B2M-Ag01	Recombinant human B2M/CDABP0092/HDCMA22P Protein	3090
GMP-h-B2M-Ab01	Anti-human B2M/CDABP0092/HDCMA22P mouse monoclonal antibody (mAb)	1953
GMP-h-B2M-Ab02	Anti-human B2M/CDABP0092/HDCMA22P mouse monoclonal antibody (mAb)	1953
GMP-h-B2M-Ab03	Anti-human B2M/CDABP0092/HDCMA22P human monoclonal antibody (mAb)	1953
GMP-h-B2M-Ab04	Anti-human B2M/CDABP0092/HDCMA22P human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-h-B2M-Ag01
Product Name	Recombinant human B2M/CDABP0092/HDCMA22P Protein
Target/Biomarker	Beta-2 microglobulin (B2M)
Alias of Target/Biomarker	AMYLD6, IMD43, MHC1D4
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	Beta-2 microglobulin (B2M) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in B2M level test of Kidney function (renal damages) (renal disease) and related syndrome evaluation.
Tag	His
Products description	Recombinant human B2M/CDABP0092/HDCMA22P Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-B2M-Ab01, GMP-h-B2M-Ab02
Product Name	Anti-human B2M/CDABP0092/HDCMA22P mouse monoclonal antibody (mAb)
Target/Biomarker	Beta-2 microglobulin (B2M)
Alias of Target/Biomarker	AMYLD6, IMD43, MHC1D4
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Beta-2 microglobulin (B2M) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in B2M level test of Kidney function (renal damages) (renal disease) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human B2M/CDABP0092/HDCMA22P mouse monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-B2M-Ab03, GMP-h-B2M-Ab04
Product Name	Anti-human B2M/CDABP0092/HDCMA22P human monoclonal antibody (mAb)
Target/Biomarker	Beta-2 microglobulin (B2M)
Alias of Target/Biomarker	AMYLD6, IMD43, MHC1D4
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Beta-2 microglobulin (B2M) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in B2M level test of Kidney function (renal damages) (renal disease) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human B2M/CDABP0092/HDCMA22P human monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

What is Beta-2 microglobulin (B2M) test? Beta-2 microglobulin (B2M) is a protein that is found on the surface of nucleated cells (contain a nucleus) and functions as part of the immune system. This protein is routinely shed by cells into the blood and is present in most body fluids, with highest levels in the blood, generally lower levels in spinal fluid, and trace levels in urine. In the kidneys, B2M passes through blood-filtering units called the glomeruli and is then reabsorbed by the renal proximal tubules, structures that reclaim water, proteins, vitamins, minerals, and other vital substances. Normally, only small amounts of B2M are present in the urine, but when the renal tubules become damaged or diseased, B2M concentrations increase due to the decreased ability to reabsorb this protein. When the glomeruli in the kidneys are damaged, they are unable to filter out B2M, so the level in the blood rises.

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