aquaporin-4 (AQP4) antibody and antigen (Recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-AQP4-Ag01	Recombinant human AQP4 Protein	3090
GMP-h-AQP4-Ab01	Anti-human AQP4 mouse monoclonal antibody (mAb)	1953
GMP-h-AQP4-Ab02	Anti-human AQP4 mouse monoclonal antibody (mAb)	1953
GMP-h-AQP4-Ab03	Anti-human AQP4 human monoclonal antibody (mAb)	1953
GMP-h-AQP4-Ab04	Anti-human AQP4 human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-h-AQP4-Ag01
Product Name	Recombinant human AQP4 Protein
Target/Biomarker	aquaporin-4 (AQP4)
Alias of Target/Biomarker	MIWC, MLC4, WCH4, hAQP4
Expression platform	mammalian
Isotypes	Recombinant Antigen
Bioactivity validation	aquaporin-4 (AQP4) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AQP4 level test of Inflammation/autoimmune/inflammatory disease (Cerebrovascular diseases) and related syndrome evaluation.
Tag	His
Products description	Recombinant human AQP4 Protein was expressed in mammalian expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-AQP4-Ab01, GMP-h-AQP4-Ab02
Product Name	Anti-human AQP4 mouse monoclonal antibody (mAb)
Target/Biomarker	aquaporin-4 (AQP4)
Alias of Target/Biomarker	MIWC, MLC4, WCH4, hAQP4
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	aquaporin-4 (AQP4) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AQP4 level test of Inflammation/autoimmune/inflammatory disease (Cerebrovascular diseases) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human AQP4 mouse monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-AQP4-Ab03, GMP-h-AQP4-Ab04
Product Name	Anti-human AQP4 human monoclonal antibody (mAb)
Target/Biomarker	aquaporin-4 (AQP4)
Alias of Target/Biomarker	MIWC, MLC4, WCH4, hAQP4
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	aquaporin-4 (AQP4) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in AQP4 level test of Inflammation/autoimmune/inflammatory disease (Cerebrovascular diseases) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human AQP4 human monoclonal antibody (mAb) was expressed in CHO expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Approximately 75 percent of patients with neuromyelitis optica (NMO) express antibodies to the aquaporin-4 (AQP4) receptor.  Diagnosis of NMO requires the presence of longitudinally extensive acute myelitis (lesions extending over 3 or more vertebral segments) and optic neuritis.  While absence of antibodies to the AQP4 receptor does not rule out the diagnosis of NMO, presence of this antibody is diagnostic for NMO.

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