beta-amyloid 42 (Aβ42) antibody and antigen (Recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-h-Aβ42-Ag01	Recombinant human APP/Aβ42/A4/AD1 Protein	3090
GMP-h-Aβ42-Ab01	Anti-human APP/Aβ42/A4/AD1 mouse monoclonal antibody (mAb)	1953
GMP-h-Aβ42-Ab02	Anti-human APP/Aβ42/A4/AD1 mouse monoclonal antibody (mAb)	1953
GMP-h-Aβ42-Ab03	Anti-human APP/Aβ42/A4/AD1 human monoclonal antibody (mAb)	1953
GMP-h-Aβ42-Ab04	Anti-human APP/Aβ42/A4/AD1 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-h-Aβ42-Ag01
Product Name	Recombinant human APP/Aβ42/A4/AD1 Protein
Target/Biomarker	beta-amyloid 42(Aβ42)
Alias of Target/Biomarker	AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, alpha-sAPP, preA4
Expression platform	synthesized
Isotypes	NA
Bioactivity validation	beta-amyloid 42 (Aβ42) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Aβ42 level test of Neurodegenerative diseases (Alzheimer Disease (AD),Parkinson's disease(PD)) and related syndrome evaluation.
Products description	Recombinant human APP/Aβ42/A4/AD1 Protein was expressed in synthesized expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control,ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and immunonephelometry.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-Aβ42-Ab01, GMP-h-Aβ42-Ab02
Product Name	Anti-human APP/Aβ42/A4/AD1 mouse monoclonal antibody (mAb)
Target/Biomarker	beta-amyloid 42(Aβ42)
Alias of Target/Biomarker	AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, alpha-sAPP, preA4
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Human beta-amyloid 42 (Aβ42) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other beta-amyloid 42 (Aβ42) antibodies in Aβ42 level test of Neurodegenerative diseases (Alzheimer Disease (AD),Parkinson's disease(PD)) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human APP/Aβ42/A4/AD1 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-h-Aβ42-Ab03, GMP-h-Aβ42-Ab04
Product Name	Anti-human APP/Aβ42/A4/AD1 human monoclonal antibody (mAb)
Target/Biomarker	beta-amyloid 42(Aβ42)
Alias of Target/Biomarker	AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, alpha-sAPP, preA4
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Human beta-amyloid 42 (Aβ42) antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other beta-amyloid 42 (Aβ42) antibodies in Aβ42 level test of Neurodegenerative diseases (Alzheimer Disease (AD),Parkinson's disease(PD)) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human APP/Aβ42/A4/AD1 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Easily accessible biomarkers are needed for the early identification of individuals at risk of developing Alzheimer's disease (AD) in large population screening strategies. Low plasma Aβ42/40 was associated with more pronounced decline in cognitive function (measured by multiple outcomes) over time. Findings suggest that plasma Aβ42/40 may be used to identify people at risk of cognitive decline, being an alternative to more complex and expensive measures, such as positron emission tomography imaging or cerebrospinal fluid measurement.

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