Escherichia coli F18 Fim41a antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P285-Tg005-Ag01	Recombinant Escherichia coli F18 Fim41a protein	3090
GMP-VT-P285-Tg005-Ab01	Anti-Escherichia coli F18 Fim41a mouse monoclonal antibody (mAb)	1953
GMP-VT-P285-Tg005-Ab02	Anti-Escherichia coli F18 Fim41a mouse monoclonal antibody (mAb)	1953
GMP-VT-P285-Tg005-Ab03	Anti-Escherichia coli F18 Fim41a human monoclonal antibody (mAb)	1953
GMP-VT-P285-Tg005-Ab04	Anti-Escherichia coli F18 Fim41a human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-VT-P285-Tg005-Ag01
Product Name	Recombinant Escherichia coli F18 Fim41a protein
Pathogen	Capripox Virus (CPV)
Target/Biomarker	Fim41a
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Capripox Virus (CPV) Fim41a antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Capripox Virus (CPV) level test of animal Swine/Porcine/Pig with Escherichia coli F18 infection.
Tag	His
Products description	Recombinant Escherichia coli F18 Fim41a protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-VT-P285-Tg005-Ab01, GMP-VT-P285-Tg005-Ab02
Product Name	Anti-Escherichia coli F18 Fim41a mouse monoclonal antibody (mAb)
Pathogen	Capripox Virus (CPV)
Target/Biomarker	Fim41a
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Capripox Virus (CPV) Fim41a antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Capripox Virus (CPV) antibodies in Capripox Virus (CPV) level test of animal Swine/Porcine/Pig with Escherichia coli F18 infection.
Tag	mFc
Products description	Anti-Escherichia coli F18 Fim41a mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-VT-P285-Tg005-Ab03, GMP-VT-P285-Tg005-Ab04
Product Name	Anti-Escherichia coli F18 Fim41a human monoclonal antibody (mAb)
Pathogen	Capripox Virus (CPV)
Target/Biomarker	Fim41a
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Capripox Virus (CPV) Fim41a antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Capripox Virus (CPV) antibodies in Capripox Virus (CPV) level test of animal Swine/Porcine/Pig with Escherichia coli F18 infection.
Tag	hFc
Products description	Anti-Escherichia coli F18 Fim41a human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Postweaning diarrhea (PWD) affects pigs after weaning, leading to significant economic costs for the pig industry due to weight loss and mortality as well as the cost of prevention (i.e., vaccination), treatment, and handling. Enterotoxigenic Escherichia coli (ETEC) is the main etiological agent involved in PWD worldwide. The ETEC pathotypes in pigs are characterized by the expression of specific fimbrial adhesins, which mediate bacterial colonization of the gut mucosal surface. The most commonly detected types of fimbriae are F4 (K88) and F18 (F107, 2134P, and 8813). Intestinal adhesion and subsequent colonization by ETEC depend on F4- or F18-specific receptors, the presence of which is essential for ETEC to cause disease. ETEC F18 is commonly found associated with diarrhea 2 to 6 weeks after weaning. Once ETEC bacteria have adhered and colonized the small intestine, they can produce an enterotoxin(s) leading to diarrhea.

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