Chicken Astrovirus antibody and antigen (recombinant protein)

 Download 

Diagnostic anti-Chicken Astrovirus antibodies pairs and antigen for animal health (animal Chicken infectious disease white chick syndrome) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

Go to Avian/Bird/Poultry disease testing products collection >>

Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P174-Ag01	Recombinant Chicken Astrovirus protein	$3090.00
GMP-VT-P174-Ab01	Anti-Chicken Astrovirus mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P174-Ab02	Anti-Chicken Astrovirus mouse monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P174-Ag01
Product Name	Recombinant Chicken Astrovirus protein
Pathogen	Chicken Astrovirus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Chicken Astrovirus antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Chicken Astrovirus level test of animal Chicken infectious disease with white chick syndrome.
Tag	His
Product description	Recombinant Chicken Astrovirus proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P174-Ab01,GMP-VT-P174-Ab02
Pathogen	Chicken Astrovirus
Product Name	Anti-Chicken Astrovirus mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Chicken Astrovirus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Chicken Astrovirus antibodies in Chicken Astrovirus level test of animal Chicken infectious disease with white chick syndrome.
Product description	Anti-Chicken Astrovirus mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Chicken Astrovirus antibodies./td>
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Pathogen

Chicken Astrovirus is a virus that primarily infects avian species such as chickens, turkeys, and ducks. The virus is known to cause several diseases in these animals, including White Chick Syndrome and Poult Enteritis Mortality Syndrome (PEMS). These diseases can have significant economic consequences for the poultry industry due to reduced productivity and increased mortality rates.

Chicken Astrovirus is a positive-sense single-stranded RNA virus belonging to the Astroviridae family. This family consists of small, non-enveloped viruses that are approximately 28-30 nm in size. Their genome consists of a single-stranded positive-sense RNA molecule, which is approximately 6.8-7.9 kilobases in length. The genome of Chicken Astrovirus is organized as non-segmented linear RNA, which encodes for three major proteins: the capsid protein, the RNA-dependent RNA polymerase (RdRp), and a non-structural protein.

The main gene of Chicken Astrovirus is the open reading frame 1a/1b (ORF1a/1b) gene. This gene encodes for the RNA-dependent RNA polymerase protein, which plays a critical role in viral replication. The RdRp protein is highly conserved among different strains of Astroviruses, making it an ideal target for diagnostic assays.

Diagnostic methods for detecting Chicken Astrovirus infections include reverse-transcription polymerase chain reaction (RT-PCR), enzyme-linked immunosorbent assay (ELISA), and sequencing. RT-PCR is a highly sensitive and specific method that can detect low levels of viral RNA in clinical samples. ELISA is also a sensitive method that detects the presence of viral antigens in clinical samples. Sequencing of the viral genome can provide insight into the genetic diversity of different strains of Chicken Astrovirus, which can aid in the development of effective vaccines and diagnostic assays.

The pathogenesis of Chicken Astrovirus infections is not well understood. However, studies have shown that the virus primarily infects the epithelial cells lining the small intestines of birds. The virus replicates within these cells, causing damage to the intestinal mucosa and leading to diarrhea and other symptoms. The exact mechanism by which Chicken Astrovirus causes disease is not clear, and further research is needed to better understand the pathogenesis of this virus.

In conclusion, Chicken Astrovirus is a significant pathogen that primarily affects avian species such as chickens, turkeys, and ducks. The virus can cause several diseases in these animals, leading to reduced productivity and increased mortality rates. Diagnostic methods for Chicken Astrovirus infections include RT-PCR, ELISA, and sequencing. Further research is needed to better understand the pathogenesis of Chicken Astrovirus and develop effective vaccines and diagnostic assays to manage this pathogen.

About GDU