Aujeszky's disease virus antibody and antigen (recombinant protein)

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Diagnostic anti-Aujeszky's disease virus antibodies pairs and antigen for animal health (animal Swine/Porcine/Pig infectious disease Aujeszky's disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P120-Ag01	Recombinant Aujeszky's disease virus protein	$3090.00
GMP-VT-P120-Ab01	Anti-Aujeszky's disease virus mouse monoclonal antibody (mAb)	$3090.00
GMP-VT-P120-Ab02	Anti-Aujeszky's disease virus mouse monoclonal antibody (mAb)	$3090.00

Size： 1mg | 10mg | 100mg

Product Description

Cat No.	GMP-VT-P120-Ag01
Product Name	Recombinant Aujeszky's disease virus protein
Pathogen	Aujeszky's disease virus
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Aujeszky's disease virus antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Aujeszky's disease virus level test of animal Swine/Porcine/Pig infectious disease with Aujeszky's disease.
Tag	His
Product description	Recombinant Aujeszky's disease virus proteinwas expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No.	GMP-VT-P120-Ab01,GMP-VT-P120-Ab02
Pathogen	Aujeszky's disease virus
Product Name	Anti-Aujeszky's disease virus mouse monoclonal antibody (mAb)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Aujeszky's disease virus antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Aujeszky's disease virus antibodies in Aujeszky's disease virus level test of animal Swine/Porcine/Pig infectious disease with Aujeszky's disease.
Product description	Anti-Aujeszky's disease virus mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Aujeszky's disease virus antibodies./td>
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
Formulation	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Pathogen

Aujeszky's Disease Virus (ADV), also known as Pseudorabies virus, is a member of the Herpesviridae family. It is an enveloped, double-stranded DNA virus that infects pigs and other animals. In this response, we will provide an in-depth description of the pathogen, its structure, hosts, and diagnostic methods.

ADV has several structural features that contribute to its ability to infect and evade host immune responses. These structures include glycoprotein B (gB), glycoprotein C (gC), glycoprotein D (gD), and glycoprotein E (gE). The gB protein is essential for fusion of the viral envelope with the host cell membrane, while the gC protein functions as a scavenger to bind with host antibodies. The gD protein is a receptor-binding protein that allows the virus to enter the host cells, while the gE protein is involved in viral dissemination between cells and immune evasion by interacting with host immune cells.

In pigs, ADV causes Aujeszky's disease, also known as pseudorabies, which is characterized by severe neurological symptoms, including seizures, paralysis, and death. In other animals, such as dogs and cats, ADV can also cause neurological symptoms, respiratory distress, and even death. Pigs are considered to be the primary host for ADV, but it can infect a wide range of other animals, including cattle, sheep, goats, horses, deer, and even humans.

The diagnosis of ADV can be achieved through a variety of methods. Nucleic acid-based techniques, such as polymerase chain reaction (PCR) and real-time PCR, are commonly used to detect the virus. These techniques target specific genes, such as gB or gD, in order to identify the presence of the virus in infected tissues or body fluids. Additionally, virus isolation in cell culture can be performed to confirm the presence of the virus. This method involves culturing the virus in specific cells and then identifying the cytopathic effects that the virus has on the cells. Serological assays, such as enzyme-linked immunosorbent assay (ELISA), can also be used to detect anti-ADV antibodies in the blood.

In conclusion, Aujeszky's Disease Virus (ADV) is a member of the Herpesviridae family that infects pigs and other animals. ADV has several structural features that contribute to its ability to infect and evade host immune responses. Although pigs are considered the primary host, the virus can infect a wide range of other animals, including humans. Diagnosis of ADV can be performed through various techniques, including nucleic acid-based methods, virus isolation in cell culture, and serological assays. While there is no cure for ADV, vaccination has been shown to be an effective method for preventing and controlling the spread of the virus in the animal population.

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