Brucella abortus/Brucella melitensis virB5 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-VT-P100-Tg004-Ag01	Recombinant Brucella abortus/Brucella melitensis virB5 protein	3090
GMP-VT-P100-Tg004-Ab01	Anti-Brucella abortus/Brucella melitensis virB5 mouse monoclonal antibody (mAb)	1953
GMP-VT-P100-Tg004-Ab02	Anti-Brucella abortus/Brucella melitensis virB5 mouse monoclonal antibody (mAb)	1953
GMP-VT-P100-Tg004-Ab03	Anti-Brucella abortus/Brucella melitensis virB5 human monoclonal antibody (mAb)	1953
GMP-VT-P100-Tg004-Ab04	Anti-Brucella abortus/Brucella melitensis virB5 human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-VT-P100-Tg004-Ag01
Product Name	Recombinant Brucella abortus/Brucella melitensis virB5 protein
Pathogen	Brucella abortus/Brucella melitensis
Target/Biomarker	virB5
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Brucella abortus/Brucella melitensis virB5 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Brucella abortus/Brucella melitensis level test of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig with Brucella abortus/Brucella melitensis infection.
Tag	His
Products description	Recombinant Brucella abortus/Brucella melitensis virB5 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-VT-P100-Tg004-Ab01, GMP-VT-P100-Tg004-Ab02
Product Name	Anti-Brucella abortus/Brucella melitensis virB5 mouse monoclonal antibody (mAb)
Pathogen	Brucella abortus/Brucella melitensis
Target/Biomarker	virB5
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Brucella abortus/Brucella melitensis virB5 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Brucella abortus/Brucella melitensis antibodies in Brucella abortus/Brucella melitensis level test of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig with Brucella abortus/Brucella melitensis infection.
Tag	mFc
Products description	Anti-Brucella abortus/Brucella melitensis virB5 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-VT-P100-Tg004-Ab03, GMP-VT-P100-Tg004-Ab04
Product Name	Anti-Brucella abortus/Brucella melitensis virB5 human monoclonal antibody (mAb)
Pathogen	Brucella abortus/Brucella melitensis
Target/Biomarker	virB5
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Brucella abortus/Brucella melitensis virB5 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Brucella abortus/Brucella melitensis antibodies in Brucella abortus/Brucella melitensis level test of animal Bovines/Cattle, Ovines/Sheep, Caprine/Goat, Swine/Porcine/Pig with Brucella abortus/Brucella melitensis infection.
Tag	hFc
Products description	Anti-Brucella abortus/Brucella melitensis virB5 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Brucella melitensis in the adult ewe is generally asymptomatic and self-limiting within about 3 months. However, because the organism may enter and cause necrosis of the chorionic villi and fetal organs, abortion or stillbirths may occur. Abortion usually occurs in the third trimester, after which the ewe will appear to recover. It has been reported that up to 20% of infected ewes may abort more than once. Rams will also be infected and may develop orchitis or pneumonia. The disease caused by B. ovis is manifested by clinical or subclinical infection of the epididymis, leading to epididymal enlargement and testicular atrophy. Brucella ovis causes decreased fertility. Brucella melitensis is the more common cause of brucellosis in goats. Brucella abortus has been shown to infect goats in natural and experimental infections, and B. ovis has also been shown to infect goats experimentally. Does infected with B. melitensis will also abort during the third trimester. Infections with B. abortus in cattle produce few clinical signs. There may be a brief septicemia during which organisms are phagocytosed by neutrophils and fixed macrophages in lymph nodes. In cows, the organism localizes in supramammary lymph nodes and udders and in the endometrium and placenta of pregnant cows. Infection may cause abortions after the fifth month, with resulting retained placentas. Permanent infection of the udder is common and results in shedding of organisms in milk. In bulls, the organism may cause unilateral orchitis and epidydimitis and involvement of the secondary sex organs. Organisms may be in the semen. In infected herds, lameness may also be a clinical sign.

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