Hygromycin B(HMB) antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Hygromycin B(HMB) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Hygromycin B(HMB)

OVA-Hygromycin B(HMB)

Anti-Hygromycin B(HMB) mouse monoclonal antibody

Anti-Hygromycin B(HMB) human monoclonal antibody

Reference

Validation Data

Click to get more Data / Case study about the product.

Biomarker Information

Hygromycin B (HMB) in Veterinary Drug Residues and Additives:

1.1. Hygromycin B (HMB) Description:

Hygromycin B (HMB), a member of the aminoglycoside antibiotic family, is recognized for its remarkable antimicrobial properties. In veterinary practice, HMB plays a pivotal role in addressing bacterial infections in animals, particularly livestock. Its mechanism of action involves disrupting bacterial protein synthesis, rendering it effective against a broad spectrum of bacterial pathogens.

Hygromycin B, initially isolated from the soil bacterium Streptomyces hygroscopicus, consists of a complex structure that includes a deoxystreptamine ring, an aminocyclitol ring, and various glycosidic moieties. This intricate structure contributes to its bactericidal activity by binding to the ribosome and inhibiting protein synthesis, ultimately leading to bacterial cell death.

1.2. Role in Veterinary Drug Residues and Additives:

1.2.1. Disease Prevention and Therapeutic Application:

In veterinary medicine, Hygromycin B is a cornerstone in the battle against bacterial infections in animals. Its effectiveness against a wide range of bacteria makes it a versatile and valuable choice in both prevention and treatment. Veterinarians often prescribe HMB to ensure the health and well-being of livestock. By combating bacterial diseases, HMB contributes to the overall productivity and health of the animals, thereby safeguarding the interests of the agricultural industry.

1.2.2. Additive in Animal Feed:

Apart from its role as a direct therapeutic agent, Hygromycin B finds applications as an additive in animal feed. This use is particularly significant in agricultural settings, where maintaining the health of large animal populations is paramount. The addition of HMB to animal feed serves a prophylactic purpose by preventing bacterial infections and ensuring the general well-being of animals. This not only benefits the animals but also contributes to the overall success and sustainability of livestock farming operations.

2. Significance of Measuring Hygromycin B (HMB):

2.1. Quality Assurance in Veterinary Pharmaceuticals:

2.1.1. Regulatory Compliance:

The accurate and consistent measurement of Hygromycin B content in veterinary pharmaceutical formulations is imperative for regulatory compliance. Health authorities and regulatory bodies set stringent standards to ensure the quality and safety of veterinary medications. Precise quantification of HMB allows pharmaceutical companies to adhere to these standards, guaranteeing that their products provide the intended antibacterial effects. This is of paramount importance in preventing the development of antibiotic-resistant bacterial strains, a growing concern in both veterinary and human medicine.

2.1.2. Efficacy and Patient Safety:

Measuring HMB content in veterinary drugs is crucial to ensure their efficacy in treating bacterial infections in animals. Inaccurate dosing due to inconsistent HMB levels can lead to suboptimal treatment outcomes and potentially the development of resistant bacteria. Furthermore, precise measurement safeguards animal welfare by minimizing the risk of treatment failures and adverse effects, enhancing patient safety and the overall efficacy of veterinary medications.

2.2. Residue Monitoring in Animal Products:

2.2.1. Food Safety and Consumer Protection:

The measurement of Hygromycin B extends beyond pharmaceuticals to include the monitoring of residues in animal-derived products. Ensuring the safety of food products originating from animals treated with HMB-containing pharmaceuticals is essential. Rigorous testing protocols are in place to guarantee that residue levels are well below established safety thresholds. This safeguards the integrity of the food supply chain and protects consumers from potential health risks associated with antibiotic residues.

2.2.2. Regulatory Compliance:

Additionally, monitoring HMB residues aligns with regulatory requirements for acceptable residue limits in food-producing animals. Authorities such as the U.S. Food and Drug Administration (FDA) have established stringent Maximum Residue Limits (MRLs) for antibiotics like HMB in animal products. Adherence to these limits is essential to maintain food safety standards and prevent any potential harm to consumers.

2.3. Research and Development Significance:

2.3.1. Pharmacokinetics and Pharmacodynamics:

For biopharmaceutical companies involved in veterinary medicine, precise measurement of Hygromycin B is integral to research and development efforts. Understanding the pharmacokinetics and pharmacodynamics of HMB is fundamental for optimizing drug formulations, dosage regimens, and delivery systems. This knowledge contributes to the continual advancement of veterinary medicine, ensuring that treatments are not only effective but also administered in the most efficient and minimally invasive manner possible.

2.3.2. Innovation in Veterinary Pharmaceuticals:

Innovations in drug delivery methods, such as controlled release systems and novel formulations, are only possible when the pharmacological properties of HMB are well-understood. This commitment to research and development facilitates the evolution of veterinary pharmaceuticals, leading to improved treatments and better outcomes for animal health. Consequently, the precise measurement of HMB is integral to advancing veterinary medicine and achieving breakthroughs in animal health management.

In summary, Hygromycin B (HMB) plays a significant role in veterinary medicine, both as a therapeutic agent and as an additive in animal feed. Measuring HMB is crucial for maintaining regulatory compliance, ensuring the efficacy and safety of veterinary pharmaceuticals, monitoring residues in animal products, and driving innovation in the field. Accurate measurement of HMB content is the linchpin of these processes, supporting animal health, food safety, and the continued advancement of veterinary medicine.

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