Cefquinome(CEQ) antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Cefquinome(CEQ) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-SMT-65-1	1. BSA-Cefquinome(CEQ) 2. Anti-Cefquinome(CEQ) mouse monoclonal antibody	$2709.00
GMP-SMT-65-2	1. OVA-Cefquinome(CEQ) 2. Anti-Cefquinome(CEQ) mouse monoclonal antibody	$2709.00
GMP-SMT-65-3	1. BSA-Cefquinome(CEQ) 2. Anti-Cefquinome(CEQ) human monoclonal antibody	$2709.00
GMP-SMT-65-4	1. OVA-Cefquinome(CEQ) 2. Anti-Cefquinome(CEQ) human monoclonal antibody	$2709.00
GMP-SMT-65-5	1. BSA-Cefquinome(CEQ) 2. Recombinant beta-lactams sensor protein	$2709.00
GMP-SMT-65-6	1. OVA-Cefquinome(CEQ) 2. Recombinant beta-lactams sensor protein	$2709.00
GMP-SMT-65-Ag-1	BSA-Cefquinome(CEQ)	$756.00
GMP-SMT-65-Ag-2	OVA-Cefquinome(CEQ)	$756.00
GMP-SMT-65-Ab-1	Anti-Cefquinome(CEQ) mouse monoclonal antibody	$1953.00
GMP-SMT-65-Ab-2	Anti-Cefquinome(CEQ) human monoclonal antibody	$1953.00
GMP-SMT-sensor-1	Recombinant beta-lactams sensor protein	$1953.00

Size： 1mg | 10mg | 100mg

Product Description

BSA-Cefquinome(CEQ)

Cat No.	GMP-SMT-65-Ag-1
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products description	Competitive immunoassay-validated hapten-carrier conjugates BSA-Cefquinome(CEQ) with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Cefquinome(CEQ) had been validated with our anti-Hapten antibody Anti-Cefquinome(CEQ) mouse monoclonal antibody via competitive ELISA test.
Application	ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

OVA-Cefquinome(CEQ)

Cat No.	GMP-SMT-65-Ag-2
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products description	Competitive immunoassay-validated hapten-carrier conjugates OVA-Cefquinome(CEQ) with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Cefquinome(CEQ) had been validated with our anti-Hapten antibody Anti-Cefquinome(CEQ) mouse monoclonal antibody via competitive ELISA test.
Application	ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-Cefquinome(CEQ) mouse monoclonal antibody

Cat No.	GMP-SMT-65-Ab-1
Host of Antibody	Mouse IgG
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)	1-2
Products description	The anti-Hapten antibody against hapten Cefquinome(CEQ) had been validated with our hapten hapten-carrier conjugates BSA-Cefquinome(CEQ) via competitive ELISA test.
Application	ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-Cefquinome(CEQ) human monoclonal antibody

Cat No.	GMP-SMT-65-Ab-2
Host of Antibody	Human IgG1
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)	1-2
Products description	The anti-Hapten antibody against hapten Cefquinome(CEQ) had been validated with our hapten hapten-carrier conjugates BSA-Cefquinome(CEQ) via competitive ELISA test.
Application	ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Recombinant beta-lactams sensor protein

Cat No.	GMP-SMT-Sensor-1
Antigen & Antibody Name	Recombinant beta-lactams sensor protein
Expression platform	mammalian cell
Isotypes	Recombinant protein
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
Tag	mFc
Products description	Recombinant beta-lactams sensor protein was expressed in mammalian cell expression system with mFc tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Antibody in Elisa, Competitive ELISA, lateral-flow tests, and other immunoassays
Formulation	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Application development scientists of GDU (GeneMedi Diagnostics Unit) have generated and optimized the beta-lactams sensor protein with a larger linear range and better sensitivity against the beta-lactams. We tested 24 kinds of beta-lactams. Below is the competitive ELISA data of GeneMedi’s optimized beta-lactams sensor recombinant protein. For Ampicillin EC50 = 0.53 ng/ml (ppb); For Penicillin G, EC50 = 0.19 ng/ml (ppb). Our Recombinant beta-lactams sensor protein has obtained good performances, such as the stability and sensitivity.


Figure 1. GeneMedi's Recombinant beta-lactams sensor protein was validated to detect the beta-lactams (Ampicillin, Penicillin G, Cequinome, Cefapirin, Cephalexin, Ceftiofur) in ELISA.

Beta-lactams	Cross-Reactivity	Beta-lactams	Cross-Reactivity
Penicillin G	Y	Nafcillin	Y
Ampicillin	Y	Cephalothin	Y
Ceftiofur	Y	Cefapirin	Y
Cefquinome	Y	Cefoperazone	Y
Cephalosporin	Y	Cefotaxime	Y
Cephalexin	Y	Cefalotin	Y
Benzylpenicillin	Y	Cefuroxime	Y
Penicillin V	Y	Cefaclor	Y
Amoxicillin	Y	Ceftriaxone	Y
Oxacillin	Y	Cefamandole	Y
Cloxacillin	Y	Moxalactam	Y
Dicloxacillin	Y	Meropenem	Y
Kanamycin (Negative Control)	N	Tetracycline (Negative Control)	N

Table1. GeneMedi's Recombinant beta-lactams sensor protein can detect 24 kinds of beta-lactams with high sensitivity.

Click to get more Data / Case study about the product.

Biomarker Information

What is Cefquinome (CEQ) and its Role in Veterinary Drug Residues and Additives?

1.1 Cefquinome (CEQ): Cefquinome, a cephalosporin antibiotic, is a crucial component of veterinary medicine. In the realm of small molecules, CEQ stands as a potent bactericidal agent used primarily in the treatment of bacterial infections in livestock, particularly in cattle, swine, and poultry. It belongs to the cephalosporin class, characterized by its beta-lactam ring, which is vital for its antibacterial activity.

1.2 Pharmacological Action: CEQ exerts its antimicrobial properties by disrupting the synthesis of bacterial cell walls, making it effective against a broad spectrum of pathogens. This mechanism of action renders it invaluable in addressing conditions such as respiratory tract infections, mastitis, and metritis, which commonly afflict animals in commercial farming operations.

1.3 Role in Veterinary Drug Residues and Additives: The significance of Cefquinome extends to its role in managing veterinary drug residues and additives in animal-derived products. When utilized responsibly and under the guidance of veterinary professionals, CEQ plays a pivotal role in ensuring the safety and quality of products derived from animals. This extends to the mitigation of antibiotic residues, a concern of paramount importance in food safety and public health.

1.4 Food Safety and Public Health: CEQ is instrumental in addressing the issue of antibiotic residues in meat, milk, and other animal products. Excessive residues of antibiotics in these products can have severe consequences for consumers, including allergic reactions and the development of antibiotic resistance. Responsible use of Cefquinome helps to avoid these issues and safeguards the health of consumers.

1.5 Regulatory Compliance: In various countries and regions, there are strict regulations governing the use of veterinary drugs like Cefquinome. Adherence to these regulations is crucial, and CEQ usage must align with these standards. Non-compliance can lead to legal consequences for farmers and producers, highlighting the necessity of precise control over its administration.

Why Measure Cefquinome (CEQ)?

2.1 Residue Monitoring: Accurate measurement of Cefquinome residues is essential to ensure that it is being used responsibly and within safe limits. Regular monitoring prevents the occurrence of antibiotic residues in animal-derived products, such as meat and milk, that exceed permissible levels. This is a vital aspect of food safety and public health, as antibiotic residues can pose health risks to consumers.

2.2 Antibiotic Resistance Concerns: The measurement of CEQ levels also serves the purpose of evaluating the potential emergence of antibiotic-resistant bacteria. The misuse or overuse of antibiotics in animals can lead to the development of antibiotic-resistant strains of bacteria, which is a significant public health risk. By tracking CEQ usage and residues, veterinary professionals and regulatory bodies can implement strategies to mitigate the development of antimicrobial resistance.

2.3 Regulatory Compliance: The veterinary pharmaceutical industry operates under strict regulatory frameworks to ensure the responsible use of antibiotics like Cefquinome. Measuring CEQ is essential to demonstrate compliance with these regulations. Failure to adhere to these standards can result in legal consequences for farmers and producers, underscoring the importance of accurate measurement and adherence to regulations.

2.4 Animal Welfare and Consumer Confidence: Beyond regulatory concerns, measuring Cefquinome usage promotes animal welfare by preventing unnecessary antibiotic exposure in livestock. This, in turn, contributes to consumer confidence in the safety and quality of animal-derived products. Consumers need assurance that the products they purchase are free from harmful residues, and responsible Cefquinome usage plays a critical role in providing this assurance.

2.5 Sustainable Agriculture: Responsible measurement of CEQ aligns with the principles of sustainable agriculture. By ensuring that antibiotics are used only when necessary and in the correct dosages, it contributes to the long-term health and viability of livestock farming practices, reducing the risk of antibiotic-resistant bacteria while maintaining animal welfare and product safety.

This detailed content offers a comprehensive understanding of Cefquinome (CEQ) and the critical roles it plays in veterinary medicine, food safety, regulatory compliance, and public health. It caters to a specialized audience seeking in-depth information about this small molecule and its applications.

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