Ampicillin (Ampicillin, Amoxicillin,AMP) antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Ampicillin (Ampicillin, Amoxicillin,AMP) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-SMT-62-1	1. BSA-Ampicillin (Ampicillin, Amoxicillin,AMP) 2. Anti-Ampicillin (Ampicillin, Amoxicillin,AMP) mouse monoclonal antibody	$2709.00
GMP-SMT-62-2	1. OVA-Ampicillin (Ampicillin, Amoxicillin,AMP) 2. Anti-Ampicillin (Ampicillin, Amoxicillin,AMP) mouse monoclonal antibody	$2709.00
GMP-SMT-62-3	1. BSA-Ampicillin (Ampicillin, Amoxicillin,AMP) 2. Anti-Ampicillin (Ampicillin, Amoxicillin,AMP) human monoclonal antibody	$2709.00
GMP-SMT-62-4	1. OVA-Ampicillin (Ampicillin, Amoxicillin,AMP) 2. Anti-Ampicillin (Ampicillin, Amoxicillin,AMP) human monoclonal antibody	$2709.00
GMP-SMT-62-5	1. BSA-Ampicillin (Ampicillin, Amoxicillin,AMP) 2. Recombinant beta-lactams sensor protein	$2709.00
GMP-SMT-62-6	1. OVA-Ampicillin (Ampicillin, Amoxicillin,AMP) 2. Recombinant beta-lactams sensor protein	$2709.00
GMP-SMT-62-Ag-1	BSA-Ampicillin (Ampicillin, Amoxicillin,AMP)	$756.00
GMP-SMT-62-Ag-2	OVA-Ampicillin (Ampicillin, Amoxicillin,AMP)	$756.00
GMP-SMT-62-Ab-1	Anti-Ampicillin (Ampicillin, Amoxicillin,AMP) mouse monoclonal antibody	$1953.00
GMP-SMT-62-Ab-2	Anti-Ampicillin (Ampicillin, Amoxicillin,AMP) human monoclonal antibody	$1953.00
GMP-SMT-sensor-1	Recombinant beta-lactams sensor protein	$1953.00

Size： 1mg | 10mg | 100mg

Product Description

BSA-Ampicillin (Ampicillin, Amoxicillin,AMP)

Cat No.	GMP-SMT-62-Ag-1
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products description	Competitive immunoassay-validated hapten-carrier conjugates BSA-Ampicillin (Ampicillin, Amoxicillin,AMP) with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Ampicillin (Ampicillin, Amoxicillin,AMP) had been validated with our anti-Hapten antibody Anti-Ampicillin (Ampicillin, Amoxicillin,AMP) mouse monoclonal antibody via competitive ELISA test.
Application	ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

OVA-Ampicillin (Ampicillin, Amoxicillin,AMP)

Cat No.	GMP-SMT-62-Ag-2
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products description	Competitive immunoassay-validated hapten-carrier conjugates OVA-Ampicillin (Ampicillin, Amoxicillin,AMP) with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Ampicillin (Ampicillin, Amoxicillin,AMP) had been validated with our anti-Hapten antibody Anti-Ampicillin (Ampicillin, Amoxicillin,AMP) mouse monoclonal antibody via competitive ELISA test.
Application	ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-Ampicillin (Ampicillin, Amoxicillin,AMP) mouse monoclonal antibody

Cat No.	GMP-SMT-62-Ab-1
Host of Antibody	Mouse IgG
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)	0.1-0.2
Products description	The anti-Hapten antibody against hapten Ampicillin (Ampicillin, Amoxicillin,AMP) had been validated with our hapten hapten-carrier conjugates BSA-Ampicillin (Ampicillin, Amoxicillin,AMP) via competitive ELISA test.
Application	ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-Ampicillin (Ampicillin, Amoxicillin,AMP) human monoclonal antibody

Cat No.	GMP-SMT-62-Ab-2
Host of Antibody	Human IgG1
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)	0.1-0.2
Products description	The anti-Hapten antibody against hapten Ampicillin (Ampicillin, Amoxicillin,AMP) had been validated with our hapten hapten-carrier conjugates BSA-Ampicillin (Ampicillin, Amoxicillin,AMP) via competitive ELISA test.
Application	ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Recombinant beta-lactams sensor protein

Cat No.	GMP-SMT-Sensor-1
Antigen & Antibody Name	Recombinant beta-lactams sensor protein
Expression platform	mammalian cell
Isotypes	Recombinant protein
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
Tag	mFc
Products description	Recombinant beta-lactams sensor protein was expressed in mammalian cell expression system with mFc tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Antibody in Elisa, Competitive ELISA, lateral-flow tests, and other immunoassays
Formulation	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Application development scientists of GDU (GeneMedi Diagnostics Unit) have generated and optimized the beta-lactams sensor protein with a larger linear range and better sensitivity against the beta-lactams. We tested 24 kinds of beta-lactams. Below is the competitive ELISA data of GeneMedi’s optimized beta-lactams sensor recombinant protein. For Ampicillin EC50 = 0.53 ng/ml (ppb); For Penicillin G, EC50 = 0.19 ng/ml (ppb). Our Recombinant beta-lactams sensor protein has obtained good performances, such as the stability and sensitivity.


Figure 1. GeneMedi's Recombinant beta-lactams sensor protein was validated to detect the beta-lactams (Ampicillin, Penicillin G, Cequinome, Cefapirin, Cephalexin, Ceftiofur) in ELISA.

Beta-lactams	Cross-Reactivity	Beta-lactams	Cross-Reactivity
Penicillin G	Y	Nafcillin	Y
Ampicillin	Y	Cephalothin	Y
Ceftiofur	Y	Cefapirin	Y
Cefquinome	Y	Cefoperazone	Y
Cephalosporin	Y	Cefotaxime	Y
Cephalexin	Y	Cefalotin	Y
Benzylpenicillin	Y	Cefuroxime	Y
Penicillin V	Y	Cefaclor	Y
Amoxicillin	Y	Ceftriaxone	Y
Oxacillin	Y	Cefamandole	Y
Cloxacillin	Y	Moxalactam	Y
Dicloxacillin	Y	Meropenem	Y
Kanamycin (Negative Control)	N	Tetracycline (Negative Control)	N

Table1. GeneMedi's Recombinant beta-lactams sensor protein can detect 24 kinds of beta-lactams with high sensitivity.

Click to get more Data / Case study about the product.

Biomarker Information

1. What is Ampicillin (Ampicillin, Amoxicillin, AMP)?

Ampicillin, also known by its chemical abbreviation AMP, is a vital component of the beta-lactam antibiotic family. This group of antibiotics is characterized by a distinctive four-membered beta-lactam ring in their chemical structure. Ampicillin shares its lineage with another widely used antibiotic, Amoxicillin, both being semi-synthetic derivatives of penicillin. This shared ancestry means they function similarly, primarily targeting bacterial infections through their ability to inhibit cell wall synthesis.

In the veterinary context, Ampicillin plays an indispensable role as a therapeutic agent for combating bacterial infections in animals. This includes both livestock and companion animals, where bacterial diseases can significantly impact animal health and, in some cases, have zoonotic implications—meaning these diseases can be transmitted from animals to humans. Veterinary professionals employ Ampicillin to address various bacterial infections, ensuring the well-being of animals and preventing the spread of diseases.

Ampicillin can also serve as an essential additive in animal feed. This usage aims to promote animal growth, enhance feed efficiency, and, importantly, prevent bacterial infections in intensive animal husbandry. The incorporation of Ampicillin in animal feed formulations contributes to better animal health and efficient food production, addressing critical aspects of the global food supply chain.

2. Why Measure Ampicillin (Ampicillin, Amoxicillin, AMP)?

The precise measurement of Ampicillin levels is of paramount importance, and this significance extends to various scientific, regulatory, and public health aspects:

(1) Efficacy and Dosage Precision:

Accurate measurement of Ampicillin levels ensures that animals receive the optimal dosage required for effective treatment. Veterinary professionals must calculate the correct dose based on the specific infection, animal species, and individual weight. Inadequate dosing can lead to therapeutic failure, allowing the bacteria to persist or develop resistance. Conversely, excessive dosing can result in antibiotic resistance and potential adverse reactions in animals.

(2) Residue Control:

Ampicillin's administration to animals can result in the presence of its residues in animal-derived products, such as meat, milk, and eggs. Monitoring and regulating these residues are essential for safeguarding food safety. To address this, regulatory bodies establish Maximum Residue Limits (MRLs), specifying the maximum permissible concentrations of Ampicillin in food products. Compliance with these MRLs is essential to protect consumers from potential health risks associated with excessive residues in the food supply.

(3) Antibiotic Resistance Mitigation:

The overuse or inappropriate use of antibiotics, including Ampicillin, can have far-reaching consequences, particularly the development of antibiotic resistance. Ampicillin is no exception, and its misuse can lead to the emergence of antibiotic-resistant bacterial strains. This is a pressing public health concern as it limits the effectiveness of antibiotics in both animal and human medicine. By measuring Ampicillin levels and ensuring appropriate use, we contribute to the broader effort to combat antibiotic resistance, preserving the efficacy of this vital class of medications.

(4) Regulatory Compliance:

In veterinary medicine and food production, regulatory agencies have stringent guidelines governing antibiotic usage. Compliance with these regulations is essential to uphold animal health, food safety, and the fight against antibiotic resistance. Regulatory requirements often include the measurement and reporting of Ampicillin levels in various contexts, and non-compliance can result in severe penalties and potential damage to a company's reputation.

In summary, the accurate measurement of Ampicillin levels is a multifaceted endeavor that has profound implications for animal health, food safety, public health, and regulatory compliance. Its importance cannot be overstated, as it contributes to the responsible and effective use of Ampicillin in the context of veterinary medicine, food production, and the global battle against antibiotic resistance. By understanding and diligently monitoring Ampicillin levels, we advance the goals of animal welfare, sustainable food production, and safeguarding public health.

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