Sarafloxacin(SAR) antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Sarafloxacin(SAR) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Sarafloxacin(SAR)

OVA-Sarafloxacin(SAR)

Anti-Sarafloxacin(SAR) mouse monoclonal antibody

Anti-Sarafloxacin(SAR) human monoclonal antibody

Reference

Validation Data

Click to get more Data / Case study about the product.

Biomarker Information

. Sarafloxacin (SAR) - Veterinary Antibiotic and Residue Management:

Sarafloxacin (SAR) is a fluoroquinolone antibiotic that has found extensive application within the domain of veterinary medicine. Classified as a small molecule, SAR exhibits potent bactericidal properties, targeting a broad spectrum of pathogenic bacteria. This pharmaceutical agent has become integral in combatting bacterial infections prevalent in livestock and poultry, making it a cornerstone in veterinary therapeutic interventions.

2. Mechanism of Action and Spectrum of Activity:

Sarafloxacin operates through inhibition of bacterial DNA gyrase, a vital enzyme responsible for DNA replication and repair. This interference disrupts the bacterial cell's ability to divide and proliferate, ultimately leading to bacterial cell death. Moreover, SAR displays efficacy against both Gram-negative and Gram-positive bacteria, providing a versatile tool in the veterinary practitioner's arsenal.

3. Importance in Veterinary Medicine:

a. Treatment of Respiratory Infections: SAR's clinical utility extends to the treatment of respiratory infections in animals. Conditions such as pneumonia, bronchitis, and other respiratory tract infections respond favorably to SAR therapy, offering relief to afflicted animals.

b. Management of Gastrointestinal Infections: SAR proves effective against a spectrum of gastrointestinal pathogens, including E. coli, Salmonella, and Campylobacter species. Its administration aids in alleviating symptoms associated with enteric infections, promoting faster recovery.

c. Control of Urinary Tract Infections: SAR demonstrates notable efficacy in addressing urinary tract infections, commonly observed in both companion and production animals. Its ability to penetrate and concentrate within the urinary tract ensures targeted therapy against uropathogenic bacteria.

4. Residue Management and Food Safety Considerations:

a. Residual Presence in Animal-Derived Products:

SAR's pharmacokinetics necessitate vigilant monitoring, particularly due to its potential residual presence in food-producing animals. Following administration, SAR can persist in tissues and body fluids, necessitating stringent withdrawal periods to ensure compliance with established regulatory limits.

b. Regulatory Compliance and Consumer Safety:

Compliance with regulatory standards governing SAR usage is imperative to mitigate potential health risks associated with antibiotic residues. These residues can be transferred to consumable products such as meat, milk, and eggs. Stringent adherence to withdrawal periods and established maximum residue limits (MRLs) ensures the safety and quality of animal-derived products for human consumption.

5. Significance of Measuring Sarafloxacin (SAR):

a. Food Safety and Regulatory Adherence:

The accurate measurement of SAR levels is paramount in upholding the safety and quality of food products. This practice aligns with stringent regulations set forth by regulatory bodies to limit veterinary drug residues in consumables, safeguarding public health and ensuring compliance with regulatory norms.

b. Antimicrobial Stewardship and Resistance Mitigation:

Responsible monitoring of SAR levels aligns with the principle of antimicrobial stewardship. This practice aids in preventing antibiotic overuse, subsequently reducing the emergence of antibiotic-resistant strains. By preserving the effectiveness of SAR and similar drugs for veterinary use, prudent monitoring contributes to the sustained efficacy of these critical therapeutic agents.

In conclusion, the conscientious management of Sarafloxacin (SAR) within veterinary practices plays a pivotal role in ensuring food safety, regulatory adherence, and the judicious use of antibiotics. By addressing emerging concerns related to antibiotic resistance and human health, SAR stands as a crucial tool in safeguarding animal welfare and public well-being in the realm of veterinary medicine.

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