Tetracyclines antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Tetracyclines antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-SMT-52-1	1. BSA-Tetracyclines 2. Anti-Tetracyclines mouse monoclonal antibody	$2709.00
GMP-SMT-52-2	1. OVA-Tetracyclines 2. Anti-Tetracyclines mouse monoclonal antibody	$2709.00
GMP-SMT-52-3	1. BSA-Tetracyclines 2. Anti-Tetracyclines human monoclonal antibody	$2709.00
GMP-SMT-52-4	1. OVA-Tetracyclines 2. Anti-Tetracyclines human monoclonal antibody	$2709.00
GMP-SMT-52-Ag-1	BSA-Tetracyclines	$756.00
GMP-SMT-52-Ag-2	OVA-Tetracyclines	$756.00
GMP-SMT-52-Ab-1	Anti-Tetracyclines mouse monoclonal antibody	$1953.00
GMP-SMT-52-Ab-2	Anti-Tetracyclines human monoclonal antibody	$1953.00

Size： 1mg | 10mg | 100mg

Product Description

BSA-Tetracyclines

Cat No.	GMP-SMT-52-Ag-1
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products description	Competitive immunoassay-validated hapten-carrier conjugates BSA-Tetracyclines with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Tetracyclines had been validated with our anti-Hapten antibody Anti-Tetracyclines mouse monoclonal antibody via competitive ELISA test.
Application	ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

OVA-Tetracyclines

Cat No.	GMP-SMT-52-Ag-2
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody;
Products description	Competitive immunoassay-validated hapten-carrier conjugates OVA-Tetracyclines with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Tetracyclines had been validated with our anti-Hapten antibody Anti-Tetracyclines mouse monoclonal antibody via competitive ELISA test.
Application	ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-Tetracyclines mouse monoclonal antibody

Cat No.	GMP-SMT-52-Ab-1
Host of Antibody	Mouse IgG
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)	0.3-0.5
Products description	The anti-Hapten antibody against hapten Tetracyclines had been validated with our hapten hapten-carrier conjugates BSA-Tetracyclines via competitive ELISA test.
Application	ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Anti-Tetracyclines human monoclonal antibody

Cat No.	GMP-SMT-52-Ab-2
Host of Antibody	Human IgG1
Bioactivity validation	Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA);
ELISA IC50 (ppb)	0.3-0.5
Products description	The anti-Hapten antibody against hapten Tetracyclines had been validated with our hapten hapten-carrier conjugates BSA-Tetracyclines via competitive ELISA test.
Application	ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA)
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Figure: GeneMedi's GMP-SMT-48-Ab-1 is validated to detect the GMP-SMT-48-Ag-1 in ELISA. IC50=0.390 ppb.

Click to get more Data / Case study about the product.

Biomarker Information

Serial Number 1: Tetracyclines and Their Significance in Veterinary Drug Residues and Additives

Tetracyclines, a class of broad-spectrum antibiotics, are crucial in veterinary medicine for treating bacterial infections in animals. Their significance extends beyond therapeutic applications, playing a vital role in veterinary drug residues and additives. Tetracyclines, owing to their unique chemical structure and mechanism of action, inhibit bacterial protein synthesis by binding to the bacterial ribosome. This action renders them effective against a wide array of pathogens, making them indispensable in veterinary practice.

In the context of veterinary drug residues, tetracyclines can persist in animal tissues, such as muscles, liver, and kidneys, even after the cessation of treatment. This persistence raises concerns about their presence in food products derived from treated animals, such as meat and dairy. Regulatory agencies worldwide have established maximum residue limits (MRLs) for tetracyclines in food-producing animals to ensure consumer safety. Monitoring and enforcing these limits are essential to prevent adverse effects on human health, including allergic reactions and the development of antibiotic resistance.

Tetracycline-based additives, on the other hand, are incorporated into animal feed to promote growth, enhance feed efficiency, and prevent and treat infections. These additives are particularly prevalent in poultry and livestock farming. By controlling bacterial infections, these additives contribute to overall animal health and welfare. However, the precise dosages and administration protocols are critical to prevent the development of antibiotic-resistant bacteria, a growing concern in both human and veterinary medicine.

Serial Number 2: The Importance of Measuring Tetracyclines

Accurate measurement of tetracyclines is paramount for several reasons, spanning scientific research, veterinary practice, and food safety protocols.

In the realm of scientific research, tetracycline quantification serves as the cornerstone for studies investigating antibiotic pharmacokinetics and pharmacodynamics. Understanding how these antibiotics are metabolized and distributed in animal tissues aids in optimizing treatment regimens. Researchers rely on precise measurement techniques to explore the mechanisms of antibiotic resistance, facilitating the development of strategies to combat resistant bacterial strains.

In veterinary practice, dosage accuracy is critical to achieving therapeutic efficacy while minimizing the risk of adverse effects. Veterinary professionals need reliable methods for determining the appropriate tetracycline dosage based on factors such as the animal's species, weight, and the specific bacteria causing the infection. Misjudging the dosage can lead to treatment failure, prolonged illness in the animal, and the potential development of antibiotic-resistant bacteria.

Moreover, the measurement of tetracyclines is integral to quality control processes in pharmaceutical manufacturing. Pharmaceutical companies producing tetracycline-based medications must adhere to stringent quality standards to ensure the efficacy and safety of their products. Precise quantification of tetracyclines is essential in verifying the consistency of pharmaceutical formulations, guaranteeing that each dose delivers the intended therapeutic effect.

In the context of food safety, analytical methods for tetracycline measurement are indispensable. Rigorous testing of food products, especially those derived from animals, is essential to enforce regulatory limits and ensure compliance with international food safety standards. Accurate measurement techniques help identify potential sources of contamination, enabling prompt corrective actions to be taken to prevent contaminated products from reaching consumers.

In conclusion, the meticulous measurement of tetracyclines is pivotal in various domains, ranging from scientific research and veterinary medicine to pharmaceutical manufacturing and food safety. Accurate quantification not only ensures the effective treatment of bacterial infections in animals but also safeguards public health by preventing the proliferation of antibiotic-resistant bacteria and ensuring the quality and safety of food products. Your company's contributions to providing reliable anti-tetracycline antibodies and competitive antigens play a vital role in advancing research, enhancing veterinary practices, and upholding food safety standards, making a significant impact on global health and well-being.

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