Toltrazuril (Methyl Triazine) antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Toltrazuril (Methyl Triazine) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Toltrazuril (Methyl Triazine)

OVA-Toltrazuril (Methyl Triazine)

Anti-Toltrazuril (Methyl Triazine) mouse monoclonal antibody

Anti-Toltrazuril (Methyl Triazine) human monoclonal antibody

Reference

Validation Data

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Biomarker Information

Toltrazuril (Methyl Triazine) in Veterinary Drug Residues and Additives

Toltrazuril, a member of the triazine class of compounds, holds a pivotal role in the field of veterinary pharmacology, particularly in the management of coccidiosis—a parasitic infection caused by the Eimeria species of protozoa (1, 2). Coccidiosis is a pervasive threat in the livestock and poultry industry, known to inflict substantial economic losses due to decreased growth rates, reduced feed efficiency, and elevated mortality rates in infected animals (1, 3).

Toltrazuril exerts its therapeutic effect by inhibiting the development and reproduction of these protozoan parasites, thereby diminishing the severity of infection and ameliorating the overall health and growth of the affected animals (1, 3, 10). Its mechanism of action primarily involves interfering with the parasite's mitochondrial electron transport, impairing its energy metabolism, and arresting its replication and growth (11). This precise mode of action has made Toltrazuril an indispensable tool in the veterinarian's arsenal for combating coccidiosis, and it is utilized in various livestock and poultry species, including chickens, turkeys, pigs, and cattle (2, 10).

Toltrazuril in Veterinary Drug Residues and Additives:

The presence and quantification of Toltrazuril in animal-derived products, such as meat, milk, and eggs, is of paramount importance within the domain of veterinary drug residues and additives. The reasons for this vigilance are multifaceted and crucial for the well-being of both animals and consumers (4, 5).

Significance of Quantifying Toltrazuril (Methyl Triazine)

a. Food Safety and Regulatory Compliance: Accurate quantification of Toltrazuril residues in animal-derived products is not solely a matter of ensuring consumer safety but also a regulatory imperative. Regulatory authorities have established maximum residue limits (MRLs) for Toltrazuril, serving as safety thresholds that must not be surpassed in animal-derived products (4, 5). Adherence to these MRLs is obligatory to prevent potential health risks associated with the consumption of Toltrazuril-contaminated food products.

b. Disease Management and Therapeutic Efficacy: Beyond its role in disease prevention and treatment, the precise measurement of Toltrazuril levels is of paramount importance in the realm of coccidiosis management. It enables veterinarians and livestock producers to ensure that the drug is administered at the correct dosage to achieve the desired therapeutic effects (3, 6). Inaccurate dosing can have significant consequences; insufficient dosing may fail to provide the intended therapeutic benefits, while excessive dosing can lead to higher residues and potential health risks. Monitoring and maintaining optimal dosing levels are integral to coccidiosis control programs in livestock and poultry farming.

c. Product Quality Assurance: The presence of Toltrazuril residues in excess of established MRLs can have far-reaching implications for the quality and marketability of animal-derived products (4, 7). High residues may render these products unsuitable for human consumption, impacting both economic viability and public health. As such, rigorous monitoring of Toltrazuril levels is a pivotal component of quality control in the livestock and poultry industry.

d. Facilitating Research Endeavors: Beyond its practical applications, Toltrazuril plays a crucial role in the realm of research in veterinary medicine and animal science. Researchers often require highly specific and sensitive analytical tools to explore the pharmacokinetics and pharmacodynamics of Toltrazuril, enhancing our understanding of its action in animal systems (8, 9). Our biopharmaceutical company's offering of anti-small molecules antibodies and competitive antigens for Toltrazuril empowers these scientific endeavors, enabling the development of new drugs and treatment strategies for coccidiosis and other parasitic diseases (12).

In summary, Toltrazuril (Methyl Triazine) is an indispensable component of coccidiosis management in livestock and poultry. Its multifaceted role spans therapeutic efficacy, food safety, regulatory compliance, disease management, product quality assurance, and research facilitation. The precise quantification of Toltrazuril residues in animal-derived products is integral to maintaining both animal and human well-being while supporting advancements in veterinary medicine and food safety protocols.

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