Natamycin(NTM) antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Natamycin(NTM) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Natamycin(NTM)

OVA-Natamycin(NTM)

Anti-Natamycin(NTM) mouse monoclonal antibody

Anti-Natamycin(NTM) human monoclonal antibody

Reference

Validation Data

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Biomarker Information

1.Natamycin (NTM), an antifungal agent of the polyene macrolide class, is a natural compound produced by the bacterium Streptomyces natalensis. Within the domain of veterinary drug residues and additives, Natamycin fulfills a dual role - as a vital food preservative and as an agent used to combat specific fungal infections in animals.

2.Role in Veterinary Drug Residues: While Natamycin isn't typically employed as a direct veterinary pharmaceutical, it plays an essential role as a preservative, particularly in the preservation of animal-derived food products. This is especially prevalent in the production of cheese, where Natamycin serves as a protective shield against yeast and mold growth. Its primary function is to prevent the proliferation of these undesirable microorganisms, thereby extending the shelf life of dairy products and preserving their innate quality.

3.Role as an Additive: Natamycin is renowned for its safety in both human and animal consumption, subject to strict adherence to regulatory guidelines. In this capacity, Natamycin is instrumental in safeguarding the safety and quality of animal-derived comestibles, particularly those susceptible to fungal contamination. This is of paramount significance, as mold growth can lead to the production of harmful mycotoxins, posing substantial threats to both animal and human health.

4.The measurement of Natamycin (NTM) is imperative for several compelling reasons:

5.Quality Assurance: Accurate quantification of Natamycin levels in food products, especially within the dairy industry, is essential to ensure the efficacy of its preservative attributes. Proper dosage is critical to prevent mold and yeast infestations, which have the potential to compromise the quality and safety of the end product. Inaccurate dosing can lead to either ineffective preservation or, conversely, an excessive presence of Natamycin, which could affect the taste and texture of the final product.

6.Regulatory Compliance: Various regulatory authorities, such as the Food and Drug Administration (FDA) in the United States and the European Food Safety Authority (EFSA) in Europe, have set forth maximum residue limits (MRLs) for Natamycin in different food products. Regular assessment and monitoring are essential to ensure compliance with these established limits, thus avoiding inadvertent violations and the potential repercussions thereof.

7.Safety: Natamycin is deemed safe for human and animal consumption when used within established limits. Ensuring that Natamycin content remains within prescribed parameters in food products is crucial to guarantee safety, mitigating the potential for health concerns that may arise from excessive consumption. It is essential to strike a balance between effective preservation and consumer safety.

8.Shelf-Life Extension: In the realm of the food industry, meticulous measurement of Natamycin is pivotal in extending the longevity of products, thereby reducing wastage and upholding product integrity. It serves as an efficacious deterrent against spoilage and mold-related anomalies that can engender economic losses. Additionally, extended shelf life can contribute to cost savings and enhanced market competitiveness.

9.Analytical Techniques for Natamycin Measurement: The accurate measurement of Natamycin is an intricate process that employs various analytical techniques. These methods ensure that Natamycin levels are quantified with precision and that they conform to regulatory requirements. Some of the techniques commonly used include:

10.High-Performance Liquid Chromatography (HPLC): HPLC is a widely employed technique that separates and quantifies Natamycin from food samples. It provides excellent sensitivity and specificity, making it suitable for compliance testing and quality control in food production.

11.Liquid Chromatography-Mass Spectrometry (LC-MS): LC-MS combines the separation capabilities of liquid chromatography with mass spectrometry for increased accuracy and sensitivity. This technique is particularly useful in identifying Natamycin and its metabolites in complex matrices.

12.Enzyme-Linked Immunosorbent Assay (ELISA): ELISA is an immunological method that employs specific antibodies to detect and quantify Natamycin. It is often used in routine screening of food samples due to its simplicity and efficiency.

13.Thin-Layer Chromatography (TLC): TLC is a cost-effective method for qualitative assessment of Natamycin levels in food products. While it may lack the sensitivity of other techniques, it can provide a quick initial assessment.

14.Gas Chromatography (GC): GC is another separation technique that can be used for analyzing volatile compounds in food, including Natamycin. It is suitable for certain applications, particularly when combined with mass spectrometry.

The choice of analytical method depends on the specific requirements of the analysis and the equipment available in the laboratory. The accuracy of these techniques ensures that Natamycin levels are measured precisely, promoting product quality and safety.

15.Importance of Natamycin in Dairy Industry: The dairy industry relies heavily on Natamycin for several reasons. Cheese production, in particular, benefits significantly from the preservative properties of Natamycin. Here are some key aspects of Natamycin's importance in the dairy sector:

16.Mold and Yeast Control: Cheese, among other dairy products, is highly susceptible to mold and yeast contamination due to its composition and storage conditions. Natamycin acts as a potent antifungal agent, inhibiting the growth of these microorganisms. This, in turn, prevents spoilage, off-flavors, and texture degradation in cheese, extending its marketability and reducing product wastage.

17.Preservation of Quality: The use of Natamycin in cheese production preserves the sensory attributes of the final product. It helps maintain the desired texture, aroma, and taste, ensuring that consumers receive a high-quality product that aligns with their expectations.

18.Safety and Regulatory Compliance: The safety of food products is paramount. The regulatory bodies have set stringent guidelines for the use of Natamycin, including maximum residue limits (MRLs). Compliance with these regulations is vital to ensure consumer safety and to avoid legal repercussions.

19.Economic Benefits: Extending the shelf life of dairy products through Natamycin utilization reduces food waste, which is not only beneficial for the environment but also economically advantageous for manufacturers. It helps reduce losses associated with unsold or spoiled products.

20.Challenges and Considerations: While Natamycin is a valuable tool in food preservation, its use also presents certain challenges and considerations:

21.Allergen Concerns: Natamycin is generally considered safe, but individuals with specific allergies to antifungal agents may have adverse reactions. It's crucial for food manufacturers to clearly label products containing Natamycin to inform consumers and meet labeling requirements.

22.Monitoring and Testing: Regular monitoring and testing of Natamycin levels in food products are essential to ensure both safety and compliance with regulations. This requires investment in testing equipment and personnel training.

23.Sustainability: The production of Natamycin, like many pharmaceuticals, has environmental implications. Sustainable sourcing and production methods are increasingly important in the pharmaceutical and food industries.

In conclusion, Natamycin plays a pivotal role in the preservation of food products, especially in the dairy industry, where it combats mold and yeast growth, preserving product quality and extending shelf life. Accurate measurement and monitoring of Natamycin levels are essential to ensure its effectiveness, safety, and compliance with regulations. This multifaceted compound is a valuable tool in ensuring the safety and

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