Sulfadiazine(SD) antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Sulfadiazine(SD) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Sulfadiazine(SD)

OVA-Sulfadiazine(SD)

Anti-Sulfadiazine(SD) mouse monoclonal antibody

Anti-Sulfadiazine(SD) human monoclonal antibody

Reference

Validation Data

Click to get more Data / Case study about the product.

Biomarker Information

1. Sulfadiazine (SD) in Veterinary Drug Residues and Additives:

Sulfadiazine (SD), a sulfonamide antibiotic, holds a significant role in veterinary medicine regarding drug residues and additives. This antimicrobial agent, categorized under the sulfonamide class, is widely employed in veterinary practice to combat bacterial infections in animals. Veterinarians frequently prescribe SD to address various infections, encompassing respiratory, urinary, gastrointestinal diseases, mastitis, and foot rot. Furthermore, it plays a vital role in prophylactic measures, safeguarding animals from potential pathogenic exposures.

In the context of food safety and regulatory compliance, the monitoring of SD levels is of paramount importance. Regulatory authorities establish Maximum Residue Limits (MRLs) to ensure the safety of animal-derived products. The presence of excessive SD residues in meat, milk, or eggs can pose significant health risks to consumers. To adhere to these stringent standards, the utilization of rigorous measurement techniques and assays is imperative. Responsible antibiotic use, enforced through precise measurement, plays a crucial role in mitigating antibiotic resistance—a growing concern in both veterinary and human medicine.

2. Significance of Measuring Sulfadiazine (SD):

Accurate measurement of Sulfadiazine (SD) levels holds multifaceted importance:

1.Ensuring Food Safety: The meticulous monitoring and control of SD residues in animal products guarantee that food items reaching consumers are free from harmful contaminants. This upholds public health standards and minimizes potential health risks.

2.Regulatory Compliance: The adherence to established MRLs mandated by regulatory authorities is contingent upon precise measurement. Compliance with these standards is fundamental for agricultural practices and the food industry, ensuring the safe production and distribution of animal-derived products.

3.Antibiotic Stewardship: The prevention of antibiotic resistance is a paramount concern in veterinary medicine. Measuring SD levels aids in promoting judicious antibiotic use, preserving the efficacy of these vital medications. By ensuring that SD is used responsibly and in accordance with established guidelines, we can slow the development of antibiotic resistance.

4.Quality Assurance: For stakeholders in animal husbandry and food production, accurate measurement substantiates quality assurance efforts. It safeguards the integrity of products and bolsters brand reputation. Consumers and businesses alike rely on the consistency and safety of animal-derived products, underlining the significance of meticulous monitoring techniques.

3. Measuring Sulfadiazine (SD) Levels:

Accurate measurement of SD levels necessitates the employment of sophisticated analytical techniques and methodologies. Liquid chromatography and mass spectrometry (LC-MS) are often the methods of choice for detecting and quantifying SD residues in animal tissues and products.

5.Sample Preparation: The process begins with the collection and preparation of samples, which can include animal tissues (e.g., muscle, liver), milk, eggs, or other animal-derived products. Sample preparation involves extraction and purification steps to isolate SD from the sample matrix.

6.Liquid Chromatography (LC): Following sample preparation, liquid chromatography is employed to separate the various compounds present in the sample. LC is highly effective in separating SD from other components, allowing for precise analysis.

7.Mass Spectrometry (MS): Mass spectrometry is utilized to identify and quantify the separated SD molecules. MS provides a unique fingerprint of the compound, ensuring accurate identification and quantification.

8.Calibration Standards: To determine the concentration of SD in a sample, calibration standards with known SD concentrations are used. These standards allow for the creation of a calibration curve, which is then used to quantify the SD levels in the test samples.

9.Reporting and Compliance: The results of SD measurements are reported, and the levels are compared to established MRLs. Any samples exceeding these limits may be subject to regulatory actions.

4. The Role of Research and Technology:

Ongoing research in the field of veterinary medicine and analytical chemistry is crucial for refining measurement techniques and understanding the impact of SD residues on animal and human health. Advances in technology have led to the development of more sensitive and accurate analytical methods, enhancing our ability to detect and quantify SD in animal-derived products. Additionally, research contributes to the establishment of appropriate MRLs that strike a balance between food safety and responsible antibiotic use.

In conclusion, the scientific scrutiny of Sulfadiazine (SD) and its precise measurement techniques are indispensable facets of modern veterinary practices and the broader agricultural landscape. They safeguard both animal and human well-being by ensuring the safety of animal-derived products, promoting antibiotic stewardship, and upholding public health standards. Through continued research and technological advancements, we can further enhance our ability to monitor and control SD residues, contributing to the overall health and safety of the food supply chain.

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