Ivermectin (IVM) antibody/antigen (BSA/OVA/KLH conjugated hapten)
anti-Ivermectin (IVM) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-SMT-27-1 | 1. BSA-Ivermectin (IVM) 2. Anti-Ivermectin (IVM) mouse monoclonal antibody | $2709.00 |
GMP-SMT-27-2 | 1. OVA-Ivermectin (IVM) 2. Anti-Ivermectin (IVM) mouse monoclonal antibody | $2709.00 |
GMP-SMT-27-3 | 1. BSA-Ivermectin (IVM) 2. Anti-Ivermectin (IVM) human monoclonal antibody | $2709.00 |
GMP-SMT-27-4 | 1. OVA-Ivermectin (IVM) 2. Anti-Ivermectin (IVM) human monoclonal antibody | $2709.00 |
GMP-SMT-27-Ag-1 | BSA-Ivermectin (IVM) | $756.00 |
GMP-SMT-27-Ag-2 | OVA-Ivermectin (IVM) | $756.00 |
GMP-SMT-27-Ab-1 | Anti-Ivermectin (IVM) mouse monoclonal antibody | $1953.00 |
GMP-SMT-27-Ab-2 | Anti-Ivermectin (IVM) human monoclonal antibody | $1953.00 |
Size: 1mg | 10mg | 100mg
Product Description
BSA-Ivermectin (IVM)
Cat No. | GMP-SMT-27-Ag-1 |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; |
Products description | Competitive immunoassay-validated hapten-carrier conjugates BSA-Ivermectin (IVM) with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Ivermectin (IVM) had been validated with our anti-Hapten antibody Anti-Ivermectin (IVM) mouse monoclonal antibody via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
OVA-Ivermectin (IVM)
Cat No. | GMP-SMT-27-Ag-2 |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; |
Products description | Competitive immunoassay-validated hapten-carrier conjugates OVA-Ivermectin (IVM) with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Ivermectin (IVM) had been validated with our anti-Hapten antibody Anti-Ivermectin (IVM) mouse monoclonal antibody via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Anti-Ivermectin (IVM) mouse monoclonal antibody
Cat No. | GMP-SMT-27-Ab-1 |
Host of Antibody | Mouse IgG |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA); |
ELISA IC50 (ppb) | 3-4 |
Products description | The anti-Hapten antibody against hapten Ivermectin (IVM) had been validated with our hapten hapten-carrier conjugates BSA-Ivermectin (IVM) via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Anti-Ivermectin (IVM) human monoclonal antibody
Cat No. | GMP-SMT-27-Ab-2 |
Host of Antibody | Human IgG1 |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA); |
ELISA IC50 (ppb) | 3-4 |
Products description | The anti-Hapten antibody against hapten Ivermectin (IVM) had been validated with our hapten hapten-carrier conjugates BSA-Ivermectin (IVM) via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Biomarker Information
1. Tilmicosin (TIM) in Veterinary Drug Residues and Additives:
Tilmicosin (TIM), denoted as serial number 1, holds a pivotal place in veterinary medicine due to its effectiveness against respiratory infections in livestock, primarily cattle and swine. As a macrolide antibiotic, it inhibits bacterial protein synthesis, making it a potent weapon against conditions like bovine respiratory disease (BRD) and enzootic pneumonia. However, its significance goes beyond treating diseases; TIM's presence in animal-derived food products necessitates meticulous monitoring.
2. The Significance of Measuring Tilmicosin (TIM):
Serial number 2 focuses on the crucial reasons behind measuring Tilmicosin in various matrices, delving into the scientific intricacies of this process.
1.Residue Control: Accurate measurement of TIM is essential to monitor and control its residues in animal tissues. This is critical for ensuring that animals are safe for consumption after treatment. Adherence to prescribed withdrawal periods is vital to prevent the presence of excessive residues, which could pose health risks.
2.Food Safety Assurance: Precise quantification of Tilmicosin residues is fundamental for guaranteeing food safety. Excessive residues in food products can lead to adverse health effects in consumers, making it imperative to have stringent testing protocols in place.
3.Regulatory Compliance: Adherence to maximum residue limits (MRLs) set by regulatory bodies is mandatory for all veterinary drugs, including TIM. Serial number 2 emphasizes the importance of monitoring TIM levels to comply with these regulations, avoiding legal consequences, and ensuring seamless trade practices. In-depth analysis and documentation of TIM levels are necessary to meet the stringent criteria established by regulatory authorities worldwide.
4.Quality Assurance: In pharmaceutical and biopharmaceutical industries, maintaining the quality and efficacy of veterinary drug products is paramount. Serial number 2 discusses the role of precise TIM measurement in quality assurance protocols. Rigorous testing procedures are implemented to guarantee that veterinary drugs containing TIM are potent, safe, and devoid of contaminants.
3. Analytical Techniques for Tilmicosin Measurement:
Serial number 3 introduces various analytical techniques employed for measuring Tilmicosin residues. These techniques are continuously evolving to enhance sensitivity, accuracy, and efficiency.
5.High-Performance Liquid Chromatography (HPLC): HPLC is a widely used technique for TIM analysis. It separates compounds in a liquid sample based on their interactions with a chromatographic column. Detection methods such as UV or fluorescence spectroscopy enable precise quantification of TIM residues.
6.Liquid Chromatography-Mass Spectrometry (LC-MS): LC-MS combines the separation capabilities of liquid chromatography with the detection power of mass spectrometry. Serial number 3 emphasizes the sensitivity of this technique, making it suitable for trace-level analysis of TIM residues in complex matrices.
7.Enzyme-Linked Immunosorbent Assay (ELISA): ELISA is a rapid and cost-effective method for TIM detection. It relies on the specific binding of antibodies to TIM molecules, allowing quantitative measurement. While not as sensitive as chromatographic methods, ELISA finds utility in large-scale screening programs.
8.Gas Chromatography-Mass Spectrometry (GC-MS): GC-MS separates and analyzes compounds based on their vaporization properties. Serial number 3 highlights its suitability for volatile and semi-volatile compounds, making it applicable for certain TIM derivatives.
In conclusion, the meticulous measurement of Tilmicosin (TIM) residues is essential for safeguarding both animal and human health. Through rigorous analytical techniques and adherence to regulatory guidelines, veterinary practitioners and pharmaceutical industries ensure the responsible use of TIM while maintaining the integrity of the food supply chain. The continuous advancement of analytical methods underscores the commitment to precision, accuracy, and safety in the field of veterinary drug monitoring.The expanded description above provides detailed insights into the significance of measuring Tilmicosin (TIM) residues in veterinary medicine and food safety. By exploring the reasons behind monitoring TIM levels, regulatory compliance, and the analytical techniques involved, the content delves into the scientific intricacies of this essential process. This comprehensive overview not only enhances the understanding of readers but also caters to the need for detailed information in scientific and regulatory contexts.
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