Tylosin(TYL) antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Tylosin(TYL) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Tylosin(TYL)

OVA-Tylosin(TYL)

Anti-Tylosin(TYL) mouse monoclonal antibody

Anti-Tylosin(TYL) human monoclonal antibody

Reference

Validation Data

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Biomarker Information

1. Ivermectin (IVM) in Veterinary Drug Residues and Additives

Ivermectin (IVM) is a prominent macrocyclic lactone compound with a pivotal role in the realm of veterinary pharmacology. As part of the avermectin class of drugs, IVM is celebrated for its anthelmintic and ectoparasiticidal properties. This versatile molecule effectively combats a wide spectrum of parasitic organisms, including gastrointestinal nematodes, lungworms, mites, and ticks. Its use significantly enhances the health and productivity of livestock and companion animals, making it an indispensable tool in veterinary medicine (1).

In the context of veterinary drug residues and additives, Ivermectin holds particular importance and necessitates a meticulous approach to its administration and monitoring for several compelling reasons:

2. Animal Health and Welfare:

Ivermectin is a potent ally in eradicating parasitic infestations, thereby ensuring the overall health and welfare of animals. However, administering the right dosage and monitoring IVM levels is essential to optimize treatment regimens and avert the development of resistance in parasitic organisms (2).

3. Food Safety:

Strict regulations govern Ivermectin residues in animal-derived products, including meat, milk, eggs, and other consumables. Excessive IVM residues in these products can pose significant risks to human health. Precise quantification of Ivermectin levels is indispensable to assure the safety of these products and to ensure that they meet regulatory standards (3).

4. Regulatory Compliance:

In the veterinary and agriculture sectors, adherence to regulations is paramount. Accurate measurement of Ivermectin levels is instrumental in upholding compliance with regulatory standards and avoiding legal consequences and penalties (4).

Accurate measurement of Ivermectin levels in veterinary applications is facilitated through the utilization of specific antibodies and competitive antigens, including Carrier-coupled antigens, immunogens, hapten-carrier conjugates, BSA-conjugated compounds, and OVA-conjugated compounds (5). These specialized bioanalytical tools are integral in enabling sensitive and precise assays for Ivermectin detection and quantification. In the following sections, we will delve deeper into the mechanisms and applications of these bioanalytical tools in ensuring the safe and effective use of Ivermectin in veterinary medicine.

5. Competitive Antigens and Antibodies:

Competitive antigens and antibodies play a central role in the development of assays for Ivermectin quantification. Competitive enzyme-linked immunosorbent assays (ELISAs) and radioimmunoassays (RIAs) are commonly used methods for detecting and quantifying IVM residues in various matrices, such as animal tissues and body fluids. In these assays, a known amount of Ivermectin labeled with a detectable tag competes with the Ivermectin present in the sample for binding to specific antibodies. The amount of labeled Ivermectin that binds to the antibodies is inversely proportional to the concentration of Ivermectin in the sample.

6. Carrier-Coupled Antigens:

Carrier-coupled antigens are used in immunoassays to improve the specificity and sensitivity of Ivermectin detection. In this approach, Ivermectin is coupled

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