Avermectin(AVM) antibody/antigen (BSA/OVA/KLH conjugated hapten)
anti-Avermectin(AVM) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-SMT-24-1 | 1. BSA-Avermectin(AVM) 2. Anti-Avermectin(AVM) mouse monoclonal antibody | $2709.00 |
GMP-SMT-24-2 | 1. OVA-Avermectin(AVM) 2. Anti-Avermectin(AVM) mouse monoclonal antibody | $2709.00 |
GMP-SMT-24-3 | 1. BSA-Avermectin(AVM) 2. Anti-Avermectin(AVM) human monoclonal antibody | $2709.00 |
GMP-SMT-24-4 | 1. OVA-Avermectin(AVM) 2. Anti-Avermectin(AVM) human monoclonal antibody | $2709.00 |
GMP-SMT-24-Ag-1 | BSA-Avermectin(AVM) | $756.00 |
GMP-SMT-24-Ag-2 | OVA-Avermectin(AVM) | $756.00 |
GMP-SMT-24-Ab-1 | Anti-Avermectin(AVM) mouse monoclonal antibody | $1953.00 |
GMP-SMT-24-Ab-2 | Anti-Avermectin(AVM) human monoclonal antibody | $1953.00 |
Size: 1mg | 10mg | 100mg
Product Description
BSA-Avermectin(AVM)
Cat No. | GMP-SMT-24-Ag-1 |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; |
Products description | Competitive immunoassay-validated hapten-carrier conjugates BSA-Avermectin(AVM) with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Avermectin(AVM) had been validated with our anti-Hapten antibody Anti-Avermectin(AVM) mouse monoclonal antibody via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
OVA-Avermectin(AVM)
Cat No. | GMP-SMT-24-Ag-2 |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; |
Products description | Competitive immunoassay-validated hapten-carrier conjugates OVA-Avermectin(AVM) with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Avermectin(AVM) had been validated with our anti-Hapten antibody Anti-Avermectin(AVM) mouse monoclonal antibody via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Anti-Avermectin(AVM) mouse monoclonal antibody
Cat No. | GMP-SMT-24-Ab-1 |
Host of Antibody | Mouse IgG |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA); |
ELISA IC50 (ppb) | 2.00 |
Products description | The anti-Hapten antibody against hapten Avermectin(AVM) had been validated with our hapten hapten-carrier conjugates BSA-Avermectin(AVM) via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Anti-Avermectin(AVM) human monoclonal antibody
Cat No. | GMP-SMT-24-Ab-2 |
Host of Antibody | Human IgG1 |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA); |
ELISA IC50 (ppb) | 2.00 |
Products description | The anti-Hapten antibody against hapten Avermectin(AVM) had been validated with our hapten hapten-carrier conjugates BSA-Avermectin(AVM) via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Biomarker Information
Erythromycin (EM), a member of the macrolide antibiotic class, is a vital component of veterinary medicine and plays a significant role in maintaining animal health, ensuring food safety, and advancing pharmaceutical research. This expanded description will delve deeper into its uses, importance, and the methods for quantifying this antibiotic residue.
1.Erythromycin in Veterinary Medicine:
Erythromycin is widely employed in veterinary medicine for its efficacy in treating bacterial infections in animals. It is particularly valuable in addressing respiratory and gastrointestinal infections in livestock, poultry, and pets. The antibiotic's mechanism of action involves inhibiting bacterial protein synthesis, making it effective against a wide range of gram-positive and some gram-negative bacteria.
2.Role in Controlling and Preventing Diseases:
In the realm of veterinary medicine, Erythromycin serves as a crucial tool for controlling and preventing the spread of diseases in animals. It is administered to infected animals to combat the bacterial pathogens causing the illnesses. Furthermore, EM is often used prophylactically to prevent the emergence of bacterial infections in crowded and high-stress environments, such as in industrial farming.
3.Feed Additive for Growth Promotion:
Erythromycin is also utilized as a feed additive in animal nutrition. This application is especially common in poultry and swine farming. When added to animal feed in appropriate concentrations, EM can enhance growth and improve feed efficiency. It aids in the efficient utilization of nutrients by animals, promoting weight gain and overall health.
4.Importance of Quantification:
Accurate quantification of Erythromycin is of paramount importance for several reasons:
a. Food Safety:
One of the critical roles of quantifying EM is to ensure the safety of animal-derived products, including meat, milk, and eggs. Residues of antibiotics like Erythromycin must meet stringent safety and quality standards to be deemed suitable for human consumption. Regular monitoring and quantification are essential to verify that these products do not contain excessive antibiotic residues.
b. Regulatory Compliance:
Quantification is essential to assess compliance with regulatory guidelines pertaining to the use of veterinary drugs. Regulatory authorities set maximum residue limits (MRLs) for antibiotics like EM in animal-derived products. Accurate measurement is necessary to verify that these limits are not exceeded, which helps prevent the development of antibiotic resistance and ensures the safety of the food supply.
c. Research and Development:
Precise quantification of Erythromycin supports ongoing research and development efforts in veterinary medicine and the pharmaceutical industry. It aids in the formulation of improved antibiotics and treatment protocols. Researchers can fine-tune dosages and administration schedules, leading to more effective treatments and reduced chances of antibiotic resistance development.
d. Pharmacological Insights:
Beyond the immediate applications, quantification of Erythromycin provides valuable insights into its pharmacological properties. Understanding its concentration in animal tissues and biological fluids helps researchers study its pharmacokinetics and pharmacodynamics. This knowledge is essential for refining treatment regimens and optimizing antibiotic use.
5.Quantification Methods:
The quantification of Erythromycin in animal-derived products is typically performed using analytical techniques such as high-performance liquid chromatography (HPLC) or liquid chromatography-mass spectrometry (LC-MS). These methods allow for the accurate measurement of Erythromycin residues at low concentrations in complex matrices.
In conclusion, Erythromycin holds a significant position in veterinary medicine, where it is used to combat bacterial infections and promote animal health. Additionally, it plays a crucial role in ensuring the safety of food products and advancing pharmaceutical research. The accurate quantification of Erythromycin is essential for regulatory compliance, research, and the prevention of antibiotic resistance, making it a cornerstone in the field of veterinary medicine and animal production.
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