Chloramphenicols antibody/antigen (BSA/OVA/KLH conjugated hapten)

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anti-Chloramphenicols antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)

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Product information

Size： 1mg | 10mg | 100mg

Product Description

BSA-Chloramphenicols

OVA-Chloramphenicols

Anti-Chloramphenicols mouse monoclonal antibody

Anti-Chloramphenicols human monoclonal antibody

Reference

Validation Data

Click to get more Data / Case study about the product.

Biomarker Information

Chloramphenicol and its Role in Veterinary Drug Residues and Additives: Chloramphenicol, an antibiotic with broad-spectrum activity, has been an integral component in veterinary medicine, historically employed for treating bacterial infections across diverse livestock, including cattle, poultry, and swine (1). However, its significance in the realm of veterinary drug residues and additives is underscored by a host of complex considerations, primarily related to potential health risks associated with its use.

1.1 Residue Concerns:

Chloramphenicol's pharmacokinetics raises a critical concern regarding the persistence of the antibiotic within the animal's system post-treatment. This persistence can result in the presence of Chloramphenicol residues in animal-derived products such as meat, milk, and eggs. Of paramount concern is the potential health risk to consumers, as even minute exposures to Chloramphenicol have been associated with adverse effects, notably the development of aplastic anemia—a rare yet severe medical condition (2). Addressing this concern necessitates a comprehensive understanding of Chloramphenicol metabolism in various animal species and the establishment of stringent monitoring protocols to ensure the absence of residues in consumable products.

1.2 Regulatory Implications:

Given the potential health risks associated with Chloramphenicol residues, regulatory agencies worldwide have imposed strict bans on its use in food-producing animals. The European Union, the United States, and other nations have established Maximum Residue Limits (MRLs) to govern the allowable concentration of Chloramphenicol in food products (3). Compliance with these regulatory standards is not only essential for safeguarding public health but is also a legal imperative for producers and distributors in the food industry.

The Significance of Measuring Chloramphenicol: The measurement of Chloramphenicol levels assumes paramount significance, underpinned by a multifaceted rationale that extends beyond mere quantification.

2.1 Food Safety Assurance:

Quantifying Chloramphenicol residues in animal-derived food products is an indispensable component of ensuring food safety. Rigorous measurement protocols, often employing advanced analytical techniques such as High-Performance Liquid Chromatography (HPLC) or Enzyme-Linked Immunosorbent Assays (ELISA), provide a robust means of assessing the compliance of these products with established safety standards (4). The meticulous monitoring of Chloramphenicol levels in food products becomes a linchpin in the prevention of adverse health effects in consumers.

2.2 Regulatory Compliance:

Adherence to established regulatory standards necessitates the accurate measurement of Chloramphenicol levels. Laboratories and food production facilities must implement methodologies capable of detecting trace amounts of Chloramphenicol in diverse matrices. This compliance-driven measurement is not solely a quality assurance measure but a legal imperative, safeguarding against potential legal ramifications associated with non-compliance (5).

2.3 Quality Control in Pharmaceutical Applications:

Chloramphenicol's utility extends beyond veterinary medicine into the pharmaceutical industry, where it serves as a reference standard and raw material for the development and quality control of antibiotics. In this context, precise measurement is imperative to ensure the efficacy, safety, and quality of pharmaceutical products containing Chloramphenicol or its derivatives (6). Pharmaceutical laboratories demand accurate and reproducible measurement techniques to guarantee the reliability of their analytical methods.

2.4 Environmental Impact Assessment:

Beyond the confines of veterinary and human health, assessing Chloramphenicol levels in the environment is a crucial facet of responsible antibiotic usage. Veterinary applications of Chloramphenicol can lead to its presence in environmental matrices, such as water sources and soil. Monitoring these levels aids in evaluating the potential impact on ecosystems, helping to devise strategies for environmental protection and mitigate the ecological dispersion of this antibiotic (7). This holistic approach aligns with contemporary efforts to address the broader implications of pharmaceutical usage on environmental sustainability.

For a biopharmaceutical company specializing in anti-small molecules antibodies and competitive antigens, the provision of highly specific reagents and assays for Chloramphenicol measurement becomes not only a commercial endeavor but a scientific responsibility (8). The company plays a pivotal role in advancing research capabilities, ensuring food safety, facilitating regulatory compliance, and contributing to the broader discourse on the responsible use of antibiotics in both veterinary and pharmaceutical domains. The development and provision of cutting-edge assays that cater to the diverse needs of laboratories, regulatory bodies, and pharmaceutical manufacturers underscore the company's commitment to scientific rigor and societal well-being.

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