Nitenpyram(NIT) antibody/antigen (BSA/OVA/KLH conjugated hapten)
anti-Nitenpyram(NIT) antibody and Carrier-coupled antigen/immunogen (hapten-carrier conjugates)
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Product information
Catalog No. | Description | US $ Price (per mg) |
---|---|---|
GMP-SMT-101-1 | 1. BSA-Nitenpyram(NIT) 2. Anti-Nitenpyram(NIT) mouse monoclonal antibody | $2709.00 |
GMP-SMT-101-2 | 1. OVA-Nitenpyram(NIT) 2. Anti-Nitenpyram(NIT) mouse monoclonal antibody | $2709.00 |
GMP-SMT-101-3 | 1. BSA-Nitenpyram(NIT) 2. Anti-Nitenpyram(NIT) human monoclonal antibody | $2709.00 |
GMP-SMT-101-4 | 1. OVA-Nitenpyram(NIT) 2. Anti-Nitenpyram(NIT) human monoclonal antibody | $2709.00 |
GMP-SMT-101-Ag-1 | BSA-Nitenpyram(NIT) | $756.00 |
GMP-SMT-101-Ag-2 | OVA-Nitenpyram(NIT) | $756.00 |
GMP-SMT-101-Ab-1 | Anti-Nitenpyram(NIT) mouse monoclonal antibody | $1953.00 |
GMP-SMT-101-Ab-2 | Anti-Nitenpyram(NIT) human monoclonal antibody | $1953.00 |
Size: 1mg | 10mg | 100mg
Product Description
BSA-Nitenpyram(NIT)
Cat No. | GMP-SMT-101-Ag-1 |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; |
Products description | Competitive immunoassay-validated hapten-carrier conjugates BSA-Nitenpyram(NIT) with anti-Hapten antibody. The hapten hapten-carrier conjugates BSA-Nitenpyram(NIT) had been validated with our anti-Hapten antibody Anti-Nitenpyram(NIT) mouse monoclonal antibody via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
OVA-Nitenpyram(NIT)
Cat No. | GMP-SMT-101-Ag-2 |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; |
Products description | Competitive immunoassay-validated hapten-carrier conjugates OVA-Nitenpyram(NIT) with anti-Hapten antibody. The hapten hapten-carrier conjugates OVA-Nitenpyram(NIT) had been validated with our anti-Hapten antibody Anti-Nitenpyram(NIT) mouse monoclonal antibody via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Anti-Nitenpyram(NIT) mouse monoclonal antibody
Cat No. | GMP-SMT-101-Ab-1 |
Host of Antibody | Mouse IgG |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA); |
ELISA IC50 (ppb) | 2-3 |
Products description | The anti-Hapten antibody against hapten Nitenpyram(NIT) had been validated with our hapten hapten-carrier conjugates BSA-Nitenpyram(NIT) via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Anti-Nitenpyram(NIT) human monoclonal antibody
Cat No. | GMP-SMT-101-Ab-2 |
Host of Antibody | Human IgG1 |
Bioactivity validation | Competitive immunoassay validation (Competitive ELISA) with hapten-carrier conjugates and anti-Hapten antibody; Lateral flow immunoassay (LFIA); |
ELISA IC50 (ppb) | 2-3 |
Products description | The anti-Hapten antibody against hapten Nitenpyram(NIT) had been validated with our hapten hapten-carrier conjugates BSA-Nitenpyram(NIT) via competitive ELISA test. |
Application | ELISA tests and other immunoassays; Lateral flow immunoassay (LFIA); LTIA Immunonephelometry Time-resolved Fluorescence Immunoassay (TRFIA) |
Formulation & Reconstitution | Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O. |
Storage | Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles. |
Reference
Validation Data
Click to get more Data / Case study about the product.
Biomarker Information
1. Nitenpyram (NIT) is a small-molecule compound of utmost significance in the realm of veterinary medicine, specifically classified under veterinary drug residues and additives. This bioactive molecule is renowned for its pivotal role in addressing one of the most common and troublesome concerns among pet owners - flea infestations. It stands as a key active ingredient in various veterinary formulations meticulously crafted to combat flea infestations in domesticated animals, with a primary focus on canines and felines. Nitenpyram falls within the category of neonicotinoids, a class of chemicals celebrated for their potent neurotoxic effects on pests and, in this context, fleas. Its mechanism of action revolves around disrupting the nervous systems of fleas, culminating in paralysis and eventual mortality, thereby providing an effective solution to this persistent problem.
2. The measurement and monitoring of Nitenpyram (NIT) levels emerge as a critical practice with far-reaching implications and multiple dimensions:
a. Efficacy Assessment:
Precise quantification of Nitenpyram levels plays an instrumental role in evaluating the efficacy of veterinary flea treatments. The measurement process serves as a litmus test, enabling veterinarians and pet owners to gauge the treatment's effectiveness in eradicating fleas from afflicted animals. By tracking Nitenpyram levels before and after treatment, practitioners can ascertain whether the treatment regimen has indeed achieved the desired results.
b. Safety and Regulatory Compliance:
Nitenpyram, like other veterinary pharmaceuticals, operates within the sphere of stringent regulatory guidelines. These guidelines, often inclusive of maximum residue limits (MRLs), are designed to ensure the safety of animals receiving treatment and to safeguard the quality of derived products like meat and milk intended for human consumption. Routine monitoring of Nitenpyram levels assumes paramount importance in maintaining adherence to these regulatory stipulations. Failure to comply with these guidelines can result in potential risks to animal health and compromise the integrity of the food supply chain.
c. Residue Detection and Environmental Impact:
Beyond its direct impact on treated animals, Nitenpyram residues may potentially extend to their immediate environment, encompassing living spaces, pet bedding, and other surroundings. Monitoring Nitenpyram levels facilitates the detection of any potential environmental contamination. This aspect is of critical concern, given the broader ecological implications and potential risks to non-target species. Responsible stewardship dictates that environmental impact be monitored diligently, allowing for the timely implementation of appropriate mitigation measures.
d. Quality Control in Manufacturing:
For manufacturers in the biopharmaceutical industry producing veterinary products containing Nitenpyram, rigorous quality control is indispensable. Precise measurement of Nitenpyram levels throughout the production process serves as a quality assurance mechanism. This meticulous approach ensures that the final product maintains its intended dosage and therapeutic potency. Maintaining the correct concentration of Nitenpyram is crucial to guarantee that the end product effectively combats flea infestations among pets.
In summary, the quantitative assessment of Nitenpyram levels transcends mere measurement; it assumes paramount significance in the holistic context of evaluating the effectiveness, safety, and regulatory compliance of veterinary flea treatments. Concurrently, it stands as a bulwark for safeguarding the quality of associated biopharmaceutical products within the intricate landscape of veterinary medicine. Nitenpyram's role as a versatile tool in flea control underscores the need for vigilance and precision in its measurement, with far-reaching implications for the welfare of animals, the environment, and public health.
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