Nucleocapsid protein (Nucleocapsid) antibody and antigen (Recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-IVD-P048-Tg001-Ag01	Recombinant human SARS-CoV2 Nucleocapsid Protein	3090
GMP-IVD-P048-Tg001-Ab01	Anti-human SARS-CoV2 Nucleocapsid mouse monoclonal antibody (mAb)	1953
GMP-IVD-P048-Tg001-Ab02	Anti-human SARS-CoV2 Nucleocapsid mouse monoclonal antibody (mAb)	1953
GMP-IVD-P048-Tg001-Ab03	Anti-human SARS-CoV2 Nucleocapsid human monoclonal antibody (mAb)	1953
GMP-IVD-P048-Tg001-Ab04	Anti-human SARS-CoV2 Nucleocapsid human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-IVD-P048-Tg001-Ag01
Product Name	Recombinant human SARS-CoV2 Nucleocapsid Protein
Pathogen	SARS-CoV2
Target/Biomarker	SARS-CoV2 (Nucleocapsid)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Nucleocapsid protein (Nucleocapsid) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Nucleocapsid level test of Infectious disease (COVID-19) and related syndrome evaluation.
Tag	His
Products description	Recombinant human SARS-CoV2 Nucleocapsid Protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-IVD-P048-Tg001-Ab01, GMP-IVD-P048-Tg001-Ab02
Product Name	Anti-human SARS-CoV2 Nucleocapsid mouse monoclonal antibody (mAb)
Pathogen	SARS-CoV2
Target/Biomarker	SARS-CoV2 (Nucleocapsid)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Nucleocapsid protein (Nucleocapsid) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Nucleocapsid level test of Infectious disease (COVID-19) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human SARS-CoV2 Nucleocapsid mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-IVD-P048-Tg001-Ab03, GMP-IVD-P048-Tg001-Ab04
Product Name	Anti-human SARS-CoV2 Nucleocapsid human monoclonal antibody (mAb)
Pathogen	SARS-CoV2
Target/Biomarker	SARS-CoV2 (Nucleocapsid)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Nucleocapsid protein (Nucleocapsid) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in Nucleocapsid level test of Infectious disease (COVID-19) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human SARS-CoV2 Nucleocapsid human monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

The nucleocapsids of enveloped RNA viruses are fairly simple structures that contain only one major structural protein, often referred to as the nucleocapsid protein or core protein. This protein is usually quite basic or has a basic domain. It binds to the viral RNA and encapsidates it to form the nucleocapsid. For most RNA viruses, nucleocapsids can be recognized as distinct structures within the infected cell and can be isolated from virions by treatment with detergents that dissolve the envelope. The nucleocapsids of alphaviruses, and probably flaviviruses and arteriviruses as well, are regular icosahedral structures, and there are no other proteins within the nucleocapsid other than the nucleocapsid protein. In contrast, the nucleocapsids of all minus-strand viruses are helical and contain, in addition to the major nucleocapsid protein, two or more minor proteins that possess enzymatic activity. As described, the nucleocapsids of minus-strand RNA viruses remain intact within the cell during the entire infection cycle and serve as machines that make viral RNA. The coronaviruses also have helical nucleocapsids, but being plus-strand RNA viruses they do not need to carry enzymes in the virion to initiate infection. The helical nucleocapsids of (-) RNA viruses appear disordered within the envelope of all viruses except the rhabdoviruses, in which they are coiled in a regular fashion (see later).

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