Helicobacter pylori cytotoxin-related protein A (CagA) antibody and antigen (Recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-IVD-P044-Tg001-Ag01	Recombinant human Helicobacter pylori (H. pylori) CagA Protein	3090
GMP-IVD-P044-Tg001-Ab01	Anti-human Helicobacter pylori (H. pylori) CagA mouse monoclonal antibody (mAb)	1953
GMP-IVD-P044-Tg001-Ab02	Anti-human Helicobacter pylori (H. pylori) CagA mouse monoclonal antibody (mAb)	1953
GMP-IVD-P044-Tg001-Ab03	Anti-human Helicobacter pylori (H. pylori) CagA human monoclonal antibody (mAb)	1953
GMP-IVD-P044-Tg001-Ab04	Anti-human Helicobacter pylori (H. pylori) CagA human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-IVD-P044-Tg001-Ag01
Product Name	Recombinant human Helicobacter pylori (H. pylori) CagA Protein
Pathogen	Helicobacter pylori
Target/Biomarker	Helicobacter pylori (CagA)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Helicobacter pylori cytotoxin-related protein A (CagA) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CagA level test of Infectious disease (peptic ulcer  and gastritis) and related syndrome evaluation.
Tag	His
Products description	Recombinant human Helicobacter pylori (H. pylori) CagA Protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	positive control, ELISA test,Lateral flow immunoassay (LFIA),colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA),turbidimetric inhibition immuno assay (TINIA) and Immunonephelometry.
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-IVD-P044-Tg001-Ab01, GMP-IVD-P044-Tg001-Ab02
Product Name	Anti-human Helicobacter pylori (H. pylori) CagA mouse monoclonal antibody (mAb)
Pathogen	Helicobacter pylori
Target/Biomarker	Helicobacter pylori (CagA)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Helicobacter pylori cytotoxin-related protein A (CagA) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CagA level test of Infectious disease (peptic ulcer  and gastritis) and related syndrome evaluation.
Tag	mFc
Products description	Anti-human Helicobacter pylori (H. pylori) CagA mouse monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-IVD-P044-Tg001-Ab03, GMP-IVD-P044-Tg001-Ab04
Product Name	Anti-human Helicobacter pylori (H. pylori) CagA human monoclonal antibody (mAb)
Pathogen	Helicobacter pylori
Target/Biomarker	Helicobacter pylori (CagA)
Expression platform	CHO
Isotypes	Human lgG1
Bioactivity validation	Helicobacter pylori cytotoxin-related protein A (CagA) antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in CagA level test of Infectious disease (peptic ulcer  and gastritis) and related syndrome evaluation.
Tag	hFc
Products description	Anti-human Helicobacter pylori (H. pylori) CagA human monoclonal antibody (mAb) was expressed in CHO - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	ELISA test, Lateral flow immunoassay (LFIA), colloidal gold immunochromatographic assay, Chemiluminescent immunoassay (CLIA), turbidimetric inhibition immuno assay (TINIA), immunonephelometry and POCT
Formulation	Supplied as a 0.2 μM filtered solution of PBS,PH7.4.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

H. pylori is a Gram-negative bacterium, with which half of the world’s population is infected. This species is a Class I carcinogen that colonizes the human stomach, wherein it can induce inflammatory disorders (chronic gastritis and ulceration) and malignant neoplastic diseases (mucosa-associated lymphoid tissue and gastric cancer). The outer membrane of H. pylori plays a pivotal role in the attachment and colonization of gastric cells. After colonization, H. pylori pathogenesis results in inflammation. H. pylori-infected patients exhibit inflammation of the gastric mucosa, which can result in metaplasia. OMPs might be used as a immuno-diagnosis of H. pylori.

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