Feline TrxR antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-TrxR-Ag01	Recombinant Feline TrxR protein	3090
GMP-FEL-TrxR-Ab01	Anti-Feline TrxR mouse monoclonal antibody (mAb)	1953
GMP-FEL-TrxR-Ab02	Anti-Feline TrxR mouse monoclonal antibody (mAb)	1953
GMP-FEL-TrxR-Ab03	Anti-Feline TrxR human monoclonal antibody (mAb)	1953
GMP-FEL-TrxR-Ab04	Anti-Feline TrxR human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-TrxR-Ag01
Product Name	Recombinant Feline TrxR protein
Target/Biomarker	Feline thioredoxin reductase (SCC Ag)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline thioredoxin reductase antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SCC Ag level test of animal Cat/Feline with cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth.
Tag	His
Products description	Recombinant Feline TrxR protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-TrxR-Ab01, GMP-FEL-TrxR-Ab02
Product Name	Anti-Feline TrxR mouse monoclonal antibody (mAb)
Target/Biomarker	Feline thioredoxin reductase (SCC Ag)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline thioredoxin reductase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SCC Ag antibodies in SCC Ag level test of animal Cat/Feline with cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth.
Tag	mFc
Products description	Anti-Feline TrxR mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SCC Ag antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-TrxR-Ab03, GMP-FEL-TrxR-Ab04
Product Name	Anti-Feline TrxR human monoclonal antibody (mAb)
Target/Biomarker	Feline thioredoxin reductase (SCC Ag)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline thioredoxin reductase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SCC Ag antibodies in SCC Ag level test of animal Cat/Feline with cancer, viral disease, ischaemia– reperfusion injury, cardiac conditions, aging, premature birth.
Tag	hFc
Products description	Anti-Feline TrxR human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SCC Ag antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Feline Thioredoxin Reductase (TrxR) is an enzyme that plays a pivotal role in the intricate symphony of feline cellular biochemistry. Functionally and structurally akin to its counterparts across species, TrxR is a defender against oxidative stress—a formidable adversary that, when left unchecked, can jeopardize the vitality of feline cells. TrxR's story unfolds within the confines of feline cells, where it choreographs a complex dance of redox reactions. At its core, TrxR catalyzes the reduction of thioredoxin (Trx), a modest yet influential protein that stands as a guardian of cellular redox equilibrium. In its reduced form, Trx takes on the mantle of safeguarding cells against the malevolent influence of reactive oxygen species (ROS), diffusing their potential for oxidative harm to critical cellular components. Feline physiology is no stranger to the perpetual production of ROS. These molecules, born as natural byproducts of normal cellular metabolism, pose a continuous threat to cellular well-being. Here, TrxR emerges as a stalwart protector, ensuring that the precarious equilibrium between ROS production and detoxification remains intact. This equilibrium is essential because, like all living organisms, cats encounter ROS during everyday metabolic activities and in response to external stressors. When this balance falters, oxidative damage takes its toll, impacting essential cellular components, including lipids, proteins, and DNA.

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