Feline TSH antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-TSH-Ag01	Recombinant Feline TSH protein	3090
GMP-FEL-TSH-Ab01	Anti-Feline TSH mouse monoclonal antibody (mAb)	1953
GMP-FEL-TSH-Ab02	Anti-Feline TSH mouse monoclonal antibody (mAb)	1953
GMP-FEL-TSH-Ab03	Anti-Feline TSH human monoclonal antibody (mAb)	1953
GMP-FEL-TSH-Ab04	Anti-Feline TSH human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-TSH-Ag01
Product Name	Recombinant Feline TSH protein
Target/Biomarker	Feline Thyroid Stimulating Hormone (SAA)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Thyroid Stimulating Hormone antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SAA level test of animal Cat/Feline with Hypothyroidism, hyperthyroidism.
Tag	His
Products description	Recombinant Feline TSH protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-TSH-Ab01, GMP-FEL-TSH-Ab02
Product Name	Anti-Feline TSH mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Thyroid Stimulating Hormone (SAA)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Thyroid Stimulating Hormone antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies in SAA level test of animal Cat/Feline with Hypothyroidism, hyperthyroidism.
Tag	mFc
Products description	Anti-Feline TSH mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-TSH-Ab03, GMP-FEL-TSH-Ab04
Product Name	Anti-Feline TSH human monoclonal antibody (mAb)
Target/Biomarker	Feline Thyroid Stimulating Hormone (SAA)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline Thyroid Stimulating Hormone antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies in SAA level test of animal Cat/Feline with Hypothyroidism, hyperthyroidism.
Tag	hFc
Products description	Anti-Feline TSH human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Thyroid-Stimulating Hormone (TSH), a pivotal biomarker in cats, occupies a central role in regulating the delicate balance of feline metabolic function. Structurally, TSH is a glycoprotein hormone consisting of two subunits, alpha and beta. Its production is orchestrated by the anterior pituitary gland in response to dynamic cues from the hypothalamic-pituitary-thyroid (HPT) axis. Within the HPT axis, TSH acts as the conductor of a metabolic orchestra. Its release is initiated by the hypothalamus, specifically via thyrotropin-releasing hormone (TRH) signaling. Low circulating levels of thyroid hormones, namely triiodothyronine (T3) and thyroxine (T4), serve as potent triggers for TSH production. When these hormones are insufficient, the anterior pituitary responds by producing and releasing TSH into the bloodstream. The journey of TSH then takes it to the thyroid gland, where it binds to specific receptors on the follicular cells. This binding event sets in motion a complex cascade of intracellular processes that culminate in the synthesis and secretion of thyroid hormones—T3 and T4. These hormones, in turn, exert far-reaching effects on feline metabolism, influencing everything from energy production to thermoregulation. The precision of this regulatory system is striking. When metabolic demands surge, such as during growth, pregnancy, or exposure to cold temperatures, TSH levels rise, urging the thyroid gland to produce more thyroid hormones. This orchestrated response boosts the metabolic rate, ensuring that the cat's body generates sufficient energy to meet its needs. Conversely, during periods of metabolic slowdown, TSH levels decrease, conserving energy and resources.

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