Feline TPO antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-TPO-Ag01	Recombinant Feline TPO protein	3090
GMP-FEL-TPO-Ab01	Anti-Feline TPO mouse monoclonal antibody (mAb)	1953
GMP-FEL-TPO-Ab02	Anti-Feline TPO mouse monoclonal antibody (mAb)	1953
GMP-FEL-TPO-Ab03	Anti-Feline TPO human monoclonal antibody (mAb)	1953
GMP-FEL-TPO-Ab04	Anti-Feline TPO human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-TPO-Ag01
Product Name	Recombinant Feline TPO protein
Target/Biomarker	Feline Thyroid peroxidase (SAHH)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Thyroid peroxidase antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in SAHH level test of animal Cat/Feline with Hashimoto's disease or Graves' disease.
Tag	His
Products description	Recombinant Feline TPO protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-TPO-Ab01, GMP-FEL-TPO-Ab02
Product Name	Anti-Feline TPO mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Thyroid peroxidase (SAHH)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Thyroid peroxidase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAHH antibodies in SAHH level test of animal Cat/Feline with Hashimoto's disease or Graves' disease.
Tag	mFc
Products description	Anti-Feline TPO mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAHH antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-TPO-Ab03, GMP-FEL-TPO-Ab04
Product Name	Anti-Feline TPO human monoclonal antibody (mAb)
Target/Biomarker	Feline Thyroid peroxidase (SAHH)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline Thyroid peroxidase antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAHH antibodies in SAHH level test of animal Cat/Feline with Hashimoto's disease or Graves' disease.
Tag	hFc
Products description	Anti-Feline TPO human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-SAHH antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Thyroid Peroxidase (TPO) in cats (felines) emerges as a keystone biomarker that transcends its enzymatic role to become a linchpin of thyroid health, metabolic regulation, and overall well-being. Housed predominantly within the thyroid gland, TPO orchestrates a symphony of biochemical reactions essential to a cat's metabolic equilibrium. The defining function of TPO revolves around its enzymatic prowess, culminating in the catalysis of iodination. Specifically, TPO catalyzes the iodination of tyrosine residues residing on thyroglobulin, a substantial glycoprotein produced within the confines of thyroid follicular cells. This intricate molecular dance represents a pivotal step in the synthesis of thyroid hormones, including thyroxine (T4) and triiodothyronine (T3), which govern a myriad of physiological processes in cats. TPO's catalytic mastery unfolds through the incorporation of iodine atoms onto specific tyrosine residues within thyroglobulin. This chemical transformation begets iodinated tyrosines, which, in subsequent coupling reactions, give rise to the biologically active thyroid hormones T4 and T3. These hormones wield authoritative control over metabolic pathways, influencing energy utilization, thermoregulation, growth, and a spectrum of physiological systems within a cat's body.

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