Feline Spirochaeta antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-Spirochaeta-Ag01	Recombinant Feline Spirochaeta protein	3090
GMP-FEL-Spirochaeta-Ab01	Anti-Feline Spirochaeta mouse monoclonal antibody (mAb)	1953
GMP-FEL-Spirochaeta-Ab02	Anti-Feline Spirochaeta mouse monoclonal antibody (mAb)	1953
GMP-FEL-Spirochaeta-Ab03	Anti-Feline Spirochaeta human monoclonal antibody (mAb)	1953
GMP-FEL-Spirochaeta-Ab04	Anti-Feline Spirochaeta human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-Spirochaeta-Ag01
Product Name	Recombinant Feline Spirochaeta protein
Target/Biomarker	Feline Spirochaeta ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Spirochaeta antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Cat/Feline with N/A.
Tag	His
Products description	Recombinant Feline Spirochaeta protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-Spirochaeta-Ab01, GMP-FEL-Spirochaeta-Ab02
Product Name	Anti-Feline Spirochaeta mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Spirochaeta ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Spirochaeta antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Cat/Feline with N/A.
Tag	mFc
Products description	Anti-Feline Spirochaeta mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-Spirochaeta-Ab03, GMP-FEL-Spirochaeta-Ab04
Product Name	Anti-Feline Spirochaeta human monoclonal antibody (mAb)
Target/Biomarker	Feline Spirochaeta ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline Spirochaeta antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Cat/Feline with N/A.
Tag	hFc
Products description	Anti-Feline Spirochaeta human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Spirochetes are a group of motile bacteria, characterized by their unique helical shape, which allows them to move in a corkscrew motion. In cats (felines), spirochetes can be associated with various health conditions, although they are not as commonly reported in cats as in other species. One of the more well-known spirochetal infections in animals and humans is caused by the Borrelia species, which is responsible for Lyme disease, but direct involvement in feline health with this particular spirochete is relatively rare due to cats' apparent resistance to Lyme disease symptoms. Common Spirochetal Infections in Cats Leptospirosis: While leptospirosis is primarily known to affect dogs, cats can also be exposed to Leptospira spp., the bacteria responsible for this disease. However, cats often appear to be resistant to leptospirosis, or they may be asymptomatic carriers. The disease in mammals generally causes kidney and liver issues, but confirmed cases in cats are rare, and they are not considered a major reservoir for the bacteria. Periodontal Disease: Certain spirochetes have been implicated in periodontal disease in cats, as part of the complex bacterial community that contributes to oral infections. These bacteria can contribute to the plaque that leads to gingivitis and periodontitis. Diagnosis and Treatment Diagnosis: Diagnosing spirochetal infections in cats can involve serological tests, PCR (Polymerase Chain Reaction) assays, and microscopic examination of samples from affected tissues. For periodontal disease, a clinical examination supported by dental X-rays can help identify the extent of the problem. Treatment: Treatment for spirochetal infections may include antibiotics that are effective against these types of bacteria. For leptospirosis, although rare in cats, supportive care and treatment with appropriate antibiotics can be effective. Managing periodontal disease involves dental cleaning, possibly under anesthesia, and may require tooth extractions in severe cases. Prevention Preventive measures for spirochetal infections include controlling exposure to environments where leptospirosis could be contracted (more relevant for dogs than cats) and maintaining good oral hygiene to prevent periodontal disease. Regular veterinary check-ups are important for early detection and management of these and other health issues. In summary, while spirochetes can affect cats, the impact and prevalence of specific spirochetal diseases like leptospirosis are less significant in cats than in other animals. Nonetheless, awareness of the potential for these infections and proper veterinary care can help manage and prevent health issues associated with spirochetes in feline populations.

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