Feline S100B antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-S100B-Ag01	Recombinant Feline S100B protein	3090
GMP-FEL-S100B-Ab01	Anti-Feline S100B mouse monoclonal antibody (mAb)	1953
GMP-FEL-S100B-Ab02	Anti-Feline S100B mouse monoclonal antibody (mAb)	1953
GMP-FEL-S100B-Ab03	Anti-Feline S100B human monoclonal antibody (mAb)	1953
GMP-FEL-S100B-Ab04	Anti-Feline S100B human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-S100B-Ag01
Product Name	Recombinant Feline S100B protein
Target/Biomarker	Feline S100 proteins (S100B)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline S100 proteins antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100B level test of animal Cat/Feline with Alzheimer disease, cancer and inflammatory disorders (such as rheumatoid arthritis (RA).
Tag	His
Products description	Recombinant Feline S100B protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-S100B-Ab01, GMP-FEL-S100B-Ab02
Product Name	Anti-Feline S100B mouse monoclonal antibody (mAb)
Target/Biomarker	Feline S100 proteins (S100B)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline S100 proteins antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100B antibodies in S100B level test of animal Cat/Feline with Alzheimer disease, cancer and inflammatory disorders (such as rheumatoid arthritis (RA).
Tag	mFc
Products description	Anti-Feline S100B mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100B antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-S100B-Ab03, GMP-FEL-S100B-Ab04
Product Name	Anti-Feline S100B human monoclonal antibody (mAb)
Target/Biomarker	Feline S100 proteins (S100B)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline S100 proteins antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100B antibodies in S100B level test of animal Cat/Feline with Alzheimer disease, cancer and inflammatory disorders (such as rheumatoid arthritis (RA).
Tag	hFc
Products description	Anti-Feline S100B human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100B antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

S100B, or S100 calcium-binding protein B, is a biomarker of significant importance within the realm of cats (felines). It belongs to the S100 protein family, a diverse group of calcium-binding proteins known for their involvement in a wide range of cellular processes. In cats, S100B is primarily expressed in astrocytes, specialized glial cells that play a crucial role in maintaining the health and function of the central nervous system. S100B is distinguished by its ability to serve as a marker of neurological stress and injury. When the feline brain experiences trauma, ischemia (reduced blood supply), or neuroinflammation, S100B can be released into the bloodstream. This release can be detected through blood tests, making S100B a valuable tool for assessing the state of the central nervous system in cats. The functions of S100B in feline physiology are multifaceted. One of its prominent roles is related to neuroprotection. S100B has been shown to exert neuroprotective effects by promoting the survival and function of neurons under adverse conditions. It achieves this by regulating calcium homeostasis, influencing neuronal plasticity, and interacting with various cellular signaling pathways. These neuroprotective properties make S100B a crucial player in the brain's response to injury and stress.

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