Feline S100-A9 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-S100-A9-Ag01	Recombinant Feline S100-A9 protein	3090
GMP-FEL-S100-A9-Ab01	Anti-Feline S100-A9 mouse monoclonal antibody (mAb)	1953
GMP-FEL-S100-A9-Ab02	Anti-Feline S100-A9 mouse monoclonal antibody (mAb)	1953
GMP-FEL-S100-A9-Ab03	Anti-Feline S100-A9 human monoclonal antibody (mAb)	1953
GMP-FEL-S100-A9-Ab04	Anti-Feline S100-A9 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-S100-A9-Ag01
Product Name	Recombinant Feline S100-A9 protein
Target/Biomarker	Feline S100 Calcium Binding Protein A9 (S100-A9)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline S100 Calcium Binding Protein A9 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100-A9 level test of animal Cat/Feline with inflammatory bowel disease.
Tag	His
Products description	Recombinant Feline S100-A9 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-S100-A9-Ab01, GMP-FEL-S100-A9-Ab02
Product Name	Anti-Feline S100-A9 mouse monoclonal antibody (mAb)
Target/Biomarker	Feline S100 Calcium Binding Protein A9 (S100-A9)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline S100 Calcium Binding Protein A9 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies in S100-A9 level test of animal Cat/Feline with inflammatory bowel disease.
Tag	mFc
Products description	Anti-Feline S100-A9 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-S100-A9-Ab03, GMP-FEL-S100-A9-Ab04
Product Name	Anti-Feline S100-A9 human monoclonal antibody (mAb)
Target/Biomarker	Feline S100 Calcium Binding Protein A9 (S100-A9)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline S100 Calcium Binding Protein A9 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies in S100-A9 level test of animal Cat/Feline with inflammatory bowel disease.
Tag	hFc
Products description	Anti-Feline S100-A9 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-S100-A9 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

S100-A9 in cats (felines) is a remarkable biomarker that transcends its status to become a pivotal player in feline health, inflammation, and immunity. As a member of the S100 protein family, this calcium-binding protein holds multifaceted roles in various cellular processes, particularly those related to inflammation and immune responses. S100-A9, also known as calgranulin B, takes center stage in feline physiology, primarily produced by neutrophils and monocytes. Its significance lies in its ability to form a heterodimeric complex with S100-A8, collectively known as S100A8/A9 or calprotectin. This complex plays a pivotal role in the innate immune system's repertoire, serving as a key participant in immune regulation, host defense, and tissue homeostasis. The release of S100A8/A9 is orchestrated by activated neutrophils and monocytes, in response to inflammatory cues. This release into the extracellular environment initiates a cascade of events, where S100A8/A9 emerges as a potent pro-inflammatory mediator. Its functions include the recruitment of immune cells to sites of infection or injury, facilitating phagocytosis, and amplifying immune responses. Such versatile roles underscore its significance in feline immune defenses. However, S100-A9's influence extends beyond inflammation, encompassing a spectrum of cellular processes. It plays a pivotal role in cell adhesion, differentiation, and tissue repair. As a damage-associated molecular pattern (DAMP) molecule, S100-A9 serves as a sentinel, triggering immune responses when confronted with tissue damage or infection. This multifunctional nature highlights its significance in feline physiology, where it acts as a versatile player in immune regulation and tissue homeostasis.

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