Feline S100-A9 antibody and antigen (recombinant protein)

Diagnostic anti-Feline S100-A9 antibodies pairs and antigen for animal health (animal Cat/Feline inflammatory bowel disease) testing in ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA and POCT

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Product information

Catalog No.DescriptionUS $ Price (per mg)
GMP-FEL-S100-A9-Ag01Feline S100-A9$3090.00
GMP-FEL-S100-A9-Ab01Anti-Feline S100-A9 mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-S100-A9-Ab02Anti-Feline S100-A9 mouse monoclonal antibody (mAb)$3090.00
GMP-FEL-S100-A9-Ab03Anti-Feline S100-A9 human monoclonal antibody (mAb)$3090.00
GMP-FEL-S100-A9-Ab04Anti-Feline S100-A9 human monoclonal antibody (mAb)$3090.00

Size: 1mg | 10mg | 100mg



Product Description

Cat No. GMP-FEL-S100-A9-Ag01
Product NameFeline S100-A9
Target/BiomarkerFeline S100-A9
Expression platformE.coli
IsotypesRecombinant Antigen
Bioactivity validationAnti-Feline S100-A9 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in S100-A9 level test of animal Cat/Feline with inflammatory bowel disease.
TagHis
Reconized/Reactive SpecicsFeline S100-A9
Product descriptionRecombinant Feline S100-A9 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-S100-A9-Ab01,GMP-FEL-S100-A9-Ab02
Target/BiomarkerFeline S100-A9
Product NameAnti-Feline S100-A9 mouse monoclonal antibody (mAb)
Expression platformCHO
Isotypes Mouse IgG
Bioactivity validationRecombinant Feline S100-A9 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline S100-A9 antibodies in Feline S100-A9 level test of animal Cat/Feline with inflammatory bowel disease.
Product descriptionAnti-Feline S100-A9 mouse monoclonal antibody (mAb) is a mouse monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline S100-A9 antibodies.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Cat No.GMP-FEL-S100-A9-Ab03,GMP-FEL-S100-A9-Ab04
Target/BiomarkerFeline S100-A9
Product NameAnti-Feline S100-A9 human monoclonal antibody (mAb)
Expression platformCHO
IsotypesHuman lgG1
Bioactivity validationRecombinant Feline S100-A9 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-Feline S100-A9 antibodies in Feline S100-A9 level test of animal Cat/Feline with inflammatory bowel disease.
Product descriptionAnti-Feline S100-A9 mouse monoclonal antibody (mAb) is a human monoclonal antibody produced by CHO. The antibody is ELISA validated as capture antibody and detection antibody pair.
PurityPurity: ≥95% (SDS-PAGE)
Application Paired antibody immunoassay validation in Sandwich ELISA, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays.
FormulationLyophilized from sterile PBS, PH 7.4
StorageStore at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.


Reference




    Validation Data


    Click to get more Data / Case study about the product.



    Target/Biomarker Information


    S100-A9 in cats (felines) is a remarkable biomarker that transcends its status to become a pivotal player in feline health, inflammation, and immunity. As a member of the S100 protein family, this calcium-binding protein holds multifaceted roles in various cellular processes, particularly those related to inflammation and immune responses.

    S100-A9, also known as calgranulin B, takes center stage in feline physiology, primarily produced by neutrophils and monocytes. Its significance lies in its ability to form a heterodimeric complex with S100-A8, collectively known as S100A8/A9 or calprotectin. This complex plays a pivotal role in the innate immune system's repertoire, serving as a key participant in immune regulation, host defense, and tissue homeostasis.

    The release of S100A8/A9 is orchestrated by activated neutrophils and monocytes, in response to inflammatory cues. This release into the extracellular environment initiates a cascade of events, where S100A8/A9 emerges as a potent pro-inflammatory mediator. Its functions include the recruitment of immune cells to sites of infection or injury, facilitating phagocytosis, and amplifying immune responses. Such versatile roles underscore its significance in feline immune defenses.

    However, S100-A9's influence extends beyond inflammation, encompassing a spectrum of cellular processes. It plays a pivotal role in cell adhesion, differentiation, and tissue repair. As a damage-associated molecular pattern (DAMP) molecule, S100-A9 serves as a sentinel, triggering immune responses when confronted with tissue damage or infection. This multifunctional nature highlights its significance in feline physiology, where it acts as a versatile player in immune regulation and tissue homeostasis.



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