Feline PG I antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-PG-I-Ag01	Recombinant Feline PG I protein	3090
GMP-FEL-PG-I-Ab01	Anti-Feline PG I mouse monoclonal antibody (mAb)	1953
GMP-FEL-PG-I-Ab02	Anti-Feline PG I mouse monoclonal antibody (mAb)	1953
GMP-FEL-PG-I-Ab03	Anti-Feline PG I human monoclonal antibody (mAb)	1953
GMP-FEL-PG-I-Ab04	Anti-Feline PG I human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-PG-I-Ag01
Product Name	Recombinant Feline PG I protein
Target/Biomarker	Feline pepsinogen I (PG I)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline pepsinogen I antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PG I level test of animal Cat/Feline with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Tag	His
Products description	Recombinant Feline PG I protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-PG-I-Ab01, GMP-FEL-PG-I-Ab02
Product Name	Anti-Feline PG I mouse monoclonal antibody (mAb)
Target/Biomarker	Feline pepsinogen I (PG I)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline pepsinogen I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PG I antibodies in PG I level test of animal Cat/Feline with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Tag	mFc
Products description	Anti-Feline PG I mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PG I antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-PG-I-Ab03, GMP-FEL-PG-I-Ab04
Product Name	Anti-Feline PG I human monoclonal antibody (mAb)
Target/Biomarker	Feline pepsinogen I (PG I)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline pepsinogen I antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PG I antibodies in PG I level test of animal Cat/Feline with atrophic gastritis, pernicious anemia, intestinal metaplasia, dysplasia, gastric polyps, and gastric cancer.
Tag	hFc
Products description	Anti-Feline PG I human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PG I antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

Click to get more Data / Case study about the product.

Target/Biomarker information

Cat/Feline Pepsinogen I (PG I) emerges as an intriguing biomarker, offering a window into the world of feline digestion. Structurally, PG I is an inactive zymogen, a precursor to the active enzyme pepsin, and it takes center stage in the gastric mucosa of the feline stomach. This biomolecule is primarily produced and secreted by chief cells, specialized exocrine cells nestled within the gastric glands. The journey of PG I begins with the ingestion of food. As dietary proteins enter the stomach, PG I awaits its transformation into pepsin. This metamorphosis unfolds within the acidic environment of the gastric lumen, catalyzed by the low pH. The conversion of PG I to pepsin signifies the commencement of protein digestion, a pivotal process for nutrient absorption and overall feline health. Beyond its role as a digestive precursor, PG I serves as a sentinel for gastric health. The integrity of the gastric mucosa, where PG I is predominantly localized, is crucial for its proper secretion. Disruptions in this mucosal lining, such as those seen in gastritis or stomach ulcers, can alter PG I levels, offering valuable diagnostic clues.

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