Feline PA antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-PA-Ag01	Recombinant Feline PA protein	3090
GMP-FEL-PA-Ab01	Anti-Feline PA mouse monoclonal antibody (mAb)	1953
GMP-FEL-PA-Ab02	Anti-Feline PA mouse monoclonal antibody (mAb)	1953
GMP-FEL-PA-Ab03	Anti-Feline PA human monoclonal antibody (mAb)	1953
GMP-FEL-PA-Ab04	Anti-Feline PA human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-PA-Ag01
Product Name	Recombinant Feline PA protein
Target/Biomarker	Feline Prealbumin (PA)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Prealbumin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in PA level test of animal Cat/Feline with liver disease, inflammation, or tissue death.
Tag	His
Products description	Recombinant Feline PA protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-PA-Ab01, GMP-FEL-PA-Ab02
Product Name	Anti-Feline PA mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Prealbumin (PA)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Prealbumin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PA antibodies in PA level test of animal Cat/Feline with liver disease, inflammation, or tissue death.
Tag	mFc
Products description	Anti-Feline PA mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-PA-Ab03, GMP-FEL-PA-Ab04
Product Name	Anti-Feline PA human monoclonal antibody (mAb)
Target/Biomarker	Feline Prealbumin (PA)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline Prealbumin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PA antibodies in PA level test of animal Cat/Feline with liver disease, inflammation, or tissue death.
Tag	hFc
Products description	Anti-Feline PA human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-PA antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Feline Prothrombin Activation Fragment 1+2 (fPAF1+2) is a biochemical linchpin within the complex landscape of feline hemostasis. Structurally, it represents a fragment arising from the activation of prothrombin (Factor II) into thrombin (Factor IIa), a process governed by a cascade of coagulation factors and platelet interactions. This transformation is fundamental to the initiation of blood clot formation. Prothrombin, an inert precursor protein, circulates uneventfully in the feline bloodstream until the moment of vascular injury. When such an injury occurs, a choreographed sequence of enzymatic reactions ensues, culminating in the cleavage of prothrombin into two fragments: thrombin and fPAF1+2. Thrombin, the multifaceted enzyme that emerges from this process, occupies a pivotal role in the creation of a stable blood clot. It catalyzes the conversion of soluble fibrinogen into insoluble fibrin strands, which serve as the structural framework of a clot. While thrombin takes center stage in fibrin formation, fPAF1+2 assumes a different, yet equally critical, role. Rather than participating directly in clot assembly, it functions as an indispensable marker of ongoing thrombin generation within the feline hemostatic system. Its presence in the bloodstream serves as a dynamic reflection of the equilibrium between prothrombin activation and thrombin regulation.

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