N-terminal prohormone of brain natriuretic peptide (NT-proBNP) antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-NT-proBNP-Ag01	Recombinant Feline NT proBNP protein	3090
GMP-FEL-NT-proBNP-Ab01	Anti-Feline NT proBNP human monoclonal antibody(mAb)	1953
GMP-FEL-NT-proBNP-Ab02	Anti-Feline NT proBNP human monoclonal antibody(mAb)	1953
GMP-FEL-NT-proBNP-Ab03	Anti-Feline NT proBNP human monoclonal antibody(mAb)	1953
GMP-FEL-NT-proBNP-Ab04	Anti-Feline NT proBNP human monoclonal antibody(mAb)	1953

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Product Description

Cat No. of Products	GMP-FEL-NT-proBNP-Ag01
Product Name	Recombinant Feline NT proBNP protein
Target/Biomarker	Feline N-terminal prohormone of brain natriuretic peptide (NT proBNP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline N-terminal prohormone of brain natriuretic peptide antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in NT proBNP level test of animal Cat/Feline with Heart failure, cardiac disease.
Tag	His
Products description	Recombinant Feline NT proBNP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-NT-proBNP-Ab01, GMP-FEL-NT-proBNP-Ab02, GMP-FEL-NT-proBNP-Ab03, GMP-FEL-NT-proBNP-Ab04
Product Name	Anti-Feline NT proBNP human monoclonal antibody(mAb)
Target/Biomarker	Feline N-terminal prohormone of brain natriuretic peptide (NT proBNP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline N-terminal prohormone of brain natriuretic peptide antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NT proBNP antibodies in NT proBNP level test of animal Cat/Feline with Heart failure, cardiac disease.
Tag	mFc
Products description	Anti-Feline NT proBNP human monoclonal antibody(mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NT proBNP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

N-terminal pro-B-type natriuretic peptide (NT-proBNP) in cats is a specialized and indispensable biomarker intricately linked to cardiac health. It is derived from the B-type natriuretic peptide (BNP) precursor molecule and plays a critical role in assessing feline cardiac health. The synthesis and release of NT-proBNP in cats are intimately connected to cardiac function. Specifically, the ventricles of the heart, notably the left ventricle, are the primary source of NT-proBNP secretion. When these cardiac muscles experience stress, strain, or injury, such as in cases of hypertrophic cardiomyopathy (HCM), congestive heart failure (CHF), or other heart conditions, NT-proBNP is released into the bloodstream. NT-proBNP serves as a highly sensitive and specific indicator of cardiac stress and dysfunction in cats. Its measurement allows veterinarians to evaluate the presence and severity of various cardiac diseases, facilitating early diagnosis and tailored treatment strategies.

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