Feline NFL antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-NFL-Ag01	Recombinant Feline NFL protein	3090
GMP-FEL-NFL-Ab01	Anti-Feline NFL mouse monoclonal antibody (mAb)	1953
GMP-FEL-NFL-Ab02	Anti-Feline NFL mouse monoclonal antibody (mAb)	1953
GMP-FEL-NFL-Ab03	Anti-Feline NFL human monoclonal antibody (mAb)	1953
GMP-FEL-NFL-Ab04	Anti-Feline NFL human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-NFL-Ag01
Product Name	Recombinant Feline NFL protein
Target/Biomarker	Feline neurofilament light chain (NFL)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline neurofilament light chain antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in NFL level test of animal Cat/Feline with Alzheimer Disease(AD).
Tag	His
Products description	Recombinant Feline NFL protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-NFL-Ab01, GMP-FEL-NFL-Ab02
Product Name	Anti-Feline NFL mouse monoclonal antibody (mAb)
Target/Biomarker	Feline neurofilament light chain (NFL)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline neurofilament light chain antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NFL antibodies in NFL level test of animal Cat/Feline with Alzheimer Disease(AD).
Tag	mFc
Products description	Anti-Feline NFL mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NFL antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-NFL-Ab03, GMP-FEL-NFL-Ab04
Product Name	Anti-Feline NFL human monoclonal antibody (mAb)
Target/Biomarker	Feline neurofilament light chain (NFL)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline neurofilament light chain antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NFL antibodies in NFL level test of animal Cat/Feline with Alzheimer Disease(AD).
Tag	hFc
Products description	Anti-Feline NFL human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-NFL antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Feline Neurofilament Light Chain (NFL) emerges as a remarkable molecule in feline neurobiology, assuming a pivotal role in upholding neuronal integrity and serving as a beacon for the assessment of neurological health in cats. Structurally, NFL belongs to the neurofilament protein family and resides primarily within the axons of feline neurons. Its filamentous nature imbues it with the capacity to reinforce neuronal structural stability and support efficient electrical signal transmission. NFL's significance amplifies in the context of neuronal injury or degeneration. When neurons sustain damage, whether due to trauma, neurodegenerative diseases, or inflammatory processes, NFL is liberated from the afflicted axons. These released NFL molecules traverse the cerebrospinal fluid (CSF) and bloodstream, rendering NFL a quantifiable biomarker for neuronal damage and a valuable asset for the diagnosis and monitoring of neurological conditions in cats.

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