Feline IgG antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-IgG-Ag01	Recombinant Feline IgG protein	3090
GMP-FEL-IgG-Ab01	Anti-Feline IgG mouse monoclonal antibody (mAb)	1953
GMP-FEL-IgG-Ab02	Anti-Feline IgG mouse monoclonal antibody (mAb)	1953
GMP-FEL-IgG-Ab03	Anti-Feline IgG human monoclonal antibody (mAb)	1953
GMP-FEL-IgG-Ab04	Anti-Feline IgG human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-IgG-Ag01
Product Name	Recombinant Feline IgG protein
Target/Biomarker	Feline IgG ()
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline IgG antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in level test of animal Cat/Feline with N/A.
Tag	His
Products description	Recombinant Feline IgG protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-IgG-Ab01, GMP-FEL-IgG-Ab02
Product Name	Anti-Feline IgG mouse monoclonal antibody (mAb)
Target/Biomarker	Feline IgG ()
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline IgG antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Cat/Feline with N/A.
Tag	mFc
Products description	Anti-Feline IgG mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-IgG-Ab03, GMP-FEL-IgG-Ab04
Product Name	Anti-Feline IgG human monoclonal antibody (mAb)
Target/Biomarker	Feline IgG ()
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline IgG antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies in level test of animal Cat/Feline with N/A.
Tag	hFc
Products description	Anti-Feline IgG human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti- antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Feline Immunoglobulin G (IgG) stands as a linchpin in the intricate framework of the feline immune system. Structurally, IgG is a glycoprotein characterized by its Y-shaped configuration, comprising two identical heavy chains and two identical light chains, held together by disulfide bonds. Each IgG molecule features antigen-binding regions of extraordinary specificity, finely tuned to recognize and bind to a diverse array of pathogens. The production of IgG antibodies in cats unfolds as a meticulously orchestrated process. When B cells, a subset of white blood cells, encounter antigens—foreign substances or pathogens—they undergo activation. Subsequently, these activated B cells transform into plasma cells, specialized factories dedicated to IgG production. These plasma cells churn out copious amounts of IgG antibodies, which are then released into the bloodstream. Feline IgG antibodies exhibit remarkable versatility and precision. They possess the ability to effectively recognize and bind to a wide spectrum of pathogens, including bacteria, viruses, fungi, and parasites, through their antigen-binding regions. This interaction serves multifaceted functions, from neutralizing the invaders to activating other immune cells, facilitating pathogen clearance, and marking pathogens for destruction. One of the extraordinary attributes of Feline IgG is its role in establishing long-lasting immunity. After an initial encounter with an antigen, memory B cells are generated. These memory B cells "remember" the specific pathogen, enabling the rapid production of IgG antibodies upon subsequent exposure to the same antigen. This mechanism underpins adaptive immunity, allowing cats to mount a swift and effective response upon reencountering a pathogen.

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