Feline Haptoglobin antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-Haptoglobin-Ag01	Recombinant Feline Haptoglobin protein	3090
GMP-FEL-Haptoglobin-Ab01	Anti-Feline Haptoglobin mouse monoclonal antibody (mAb)	1953
GMP-FEL-Haptoglobin-Ab02	Anti-Feline Haptoglobin mouse monoclonal antibody (mAb)	1953
GMP-FEL-Haptoglobin-Ab03	Anti-Feline Haptoglobin human monoclonal antibody (mAb)	1953
GMP-FEL-Haptoglobin-Ab04	Anti-Feline Haptoglobin human monoclonal antibody (mAb)	1953

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Product Description

Cat No. of Products	GMP-FEL-Haptoglobin-Ag01
Product Name	Recombinant Feline Haptoglobin protein
Target/Biomarker	Feline Haptoglobin (HP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Haptoglobin antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HP level test of animal Cat/Feline with milk fever, ketosis, severe mastitis, acute severe metritis, retained placenta and chronic endometritis.
Tag	His
Products description	Recombinant Feline Haptoglobin protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-Haptoglobin-Ab01, GMP-FEL-Haptoglobin-Ab02
Product Name	Anti-Feline Haptoglobin mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Haptoglobin (HP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Haptoglobin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HP antibodies in HP level test of animal Cat/Feline with milk fever, ketosis, severe mastitis, acute severe metritis, retained placenta and chronic endometritis.
Tag	mFc
Products description	Anti-Feline Haptoglobin mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-Haptoglobin-Ab03, GMP-FEL-Haptoglobin-Ab04
Product Name	Anti-Feline Haptoglobin human monoclonal antibody (mAb)
Target/Biomarker	Feline Haptoglobin (HP)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline Haptoglobin antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HP antibodies in HP level test of animal Cat/Feline with milk fever, ketosis, severe mastitis, acute severe metritis, retained placenta and chronic endometritis.
Tag	hFc
Products description	Anti-Feline Haptoglobin human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Cat/Feline Haptoglobin is an acute phase protein that serves as a biomarker for inflammation and tissue injury in cats. In veterinary medicine, haptoglobin is measured to assess the presence and extent of inflammation, as its levels in the bloodstream rise significantly in response to tissue damage, infection, or inflammation. The utility of haptoglobin as a diagnostic marker is particularly valuable because it is not typically elevated by stress alone, which can be a confounding factor in assessing feline health. This makes haptoglobin a more specific indicator of pathological processes compared to other markers that may also increase due to stress or excitement. When a cat's body experiences inflammation, the liver is stimulated to produce higher amounts of haptoglobin. This protein functions to bind free hemoglobin released into the plasma by the destruction of red blood cells (hemolysis), thereby inhibiting its oxidative activity. The haptoglobin-hemoglobin complex is then cleared by the reticuloendothelial system, primarily in the liver and spleen. By sequestering free hemoglobin, haptoglobin prevents kidney damage and conserves iron for red blood cell production. Haptoglobin measurements are used in conjunction with other diagnostic tests to evaluate the health of cats, particularly in the presence of diseases such as infectious diseases, immune-mediated diseases, neoplasia, and various other conditions that cause systemic inflammation. It is also monitored in post-surgical patients and in those undergoing treatment for inflammatory diseases to assess the response to therapy. In feline medicine, the interpretation of haptoglobin levels must be done in the context of the overall clinical picture, as various factors can influence its concentration. Nonetheless, it remains a critical component of the panel of acute phase proteins that are routinely evaluated in cats with suspected inflammatory conditions.

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