Feline HSP90α antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-HSP90a-Ag01	Recombinant Feline HSP90α protein	3090
GMP-FEL-HSP90a-Ab01	Anti-Feline HSP90α mouse monoclonal antibody (mAb)	1953
GMP-FEL-HSP90a-Ab02	Anti-Feline HSP90α mouse monoclonal antibody (mAb)	1953
GMP-FEL-HSP90a-Ab03	Anti-Feline HSP90α human monoclonal antibody (mAb)	1953
GMP-FEL-HSP90a-Ab04	Anti-Feline HSP90α human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-HSP90a-Ag01
Product Name	Recombinant Feline HSP90α protein
Target/Biomarker	Feline Heat shock proteins 90-alpha (HSP90α)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Heat shock proteins 90-alpha antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HSP90α level test of animal Cat/Feline with renal cancer, liver cancer and breast cancer.
Tag	His
Products description	Recombinant Feline HSP90α protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-HSP90a-Ab01, GMP-FEL-HSP90a-Ab02
Product Name	Anti-Feline HSP90α mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Heat shock proteins 90-alpha (HSP90α)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Heat shock proteins 90-alpha antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HSP90α antibodies in HSP90α level test of animal Cat/Feline with renal cancer, liver cancer and breast cancer.
Tag	mFc
Products description	Anti-Feline HSP90α mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HSP90α antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-HSP90a-Ab03, GMP-FEL-HSP90a-Ab04
Product Name	Anti-Feline HSP90α human monoclonal antibody (mAb)
Target/Biomarker	Feline Heat shock proteins 90-alpha (HSP90α)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline Heat shock proteins 90-alpha antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HSP90α antibodies in HSP90α level test of animal Cat/Feline with renal cancer, liver cancer and breast cancer.
Tag	hFc
Products description	Anti-Feline HSP90α human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HSP90α antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

HSP90α, or Heat Shock Protein 90 alpha, is a biomarker of significant importance in the context of cats (felines). It belongs to the heat shock protein family, a group of molecular chaperones that play essential roles in maintaining cellular health and protein quality control. HSP90α, specifically, is predominantly localized within the cytoplasm of feline cells, where it carries out crucial functions related to protein folding, stabilization, and cellular response to stress. One of the primary roles of HSP90α is to act as a molecular chaperone, assisting in the proper folding of newly synthesized proteins. This process is essential to ensure that proteins adopt their correct three-dimensional structures, allowing them to function optimally. Moreover, HSP90α plays a role in refolding and repairing damaged or misfolded proteins. This function is particularly critical when cells face stressors that can cause proteins to misfold or aggregate, such as elevated temperatures, infections, toxins, or other environmental challenges. In response to various forms of cellular stress, the expression of HSP90α in feline cells increases significantly. This upregulation is part of the cell's adaptive response mechanism aimed at preserving protein integrity and preventing cellular dysfunction. By assisting in protein folding and repair, HSP90α helps cells cope with stress and maintain their essential functions.

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