Feline HE4 antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-HE4-Ag01	Recombinant Feline HE4 protein	3090
GMP-FEL-HE4-Ab01	Anti-Feline HE4 mouse monoclonal antibody (mAb)	1953
GMP-FEL-HE4-Ab02	Anti-Feline HE4 mouse monoclonal antibody (mAb)	1953
GMP-FEL-HE4-Ab03	Anti-Feline HE4 human monoclonal antibody (mAb)	1953
GMP-FEL-HE4-Ab04	Anti-Feline HE4 human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-HE4-Ag01
Product Name	Recombinant Feline HE4 protein
Target/Biomarker	Feline epididymis protein 4 (HE4)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline epididymis protein 4 antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HE4 level test of animal Cat/Feline with ovarian cancer.
Tag	His
Products description	Recombinant Feline HE4 protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-HE4-Ab01, GMP-FEL-HE4-Ab02
Product Name	Anti-Feline HE4 mouse monoclonal antibody (mAb)
Target/Biomarker	Feline epididymis protein 4 (HE4)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline epididymis protein 4 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HE4 antibodies in HE4 level test of animal Cat/Feline with ovarian cancer.
Tag	mFc
Products description	Anti-Feline HE4 mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HE4 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-HE4-Ab03, GMP-FEL-HE4-Ab04
Product Name	Anti-Feline HE4 human monoclonal antibody (mAb)
Target/Biomarker	Feline epididymis protein 4 (HE4)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline epididymis protein 4 antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HE4 antibodies in HE4 level test of animal Cat/Feline with ovarian cancer.
Tag	hFc
Products description	Anti-Feline HE4 human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HE4 antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Cat/Feline HE4, or Human Epididymis Protein 4, is a biomarker that has emerged as a significant focus of interest in veterinary medicine. This glycoprotein, analogous to its human counterpart, HE4, is present in cats and serves a multifaceted role in their biology. In this comprehensive description, we delve into the various aspects of Cat/Feline HE4, its significance, and its applications in feline health.Cat/Feline HE4: A Biomarker Overview HE4 is a glycoprotein expressed in cats, primarily found in their serum and tissues. Its role in feline biology has been elucidated in recent years, highlighting its importance as a biomarker for various health conditions, most notably cancer. Understanding the significance of Cat/Feline HE4 begins with exploring its diverse applications. Cancer Detection and Diagnosis One of the primary reasons for measuring Cat/Feline HE4 is its pivotal role in cancer detection and diagnosis. Elevated levels of HE4 in feline patients have been associated with various cancers, including ovarian, uterine, and lung cancer. This makes Cat/Feline HE4 a crucial tool for early cancer diagnosis in cats. In cases of ovarian cancer, HE4 has shown promise as a reliable biomarker. Cats, like humans, can develop ovarian tumors, and early detection is critical for effective treatment. Monitoring Cat/Feline HE4 levels can assist veterinarians in identifying these tumors in their nascent stages, enabling prompt intervention and potentially improving the overall prognosis. Similarly, in cases of uterine cancer, Cat/Feline HE4 can offer valuable diagnostic insights. Elevated HE4 levels may suggest the presence of uterine tumors or other abnormalities. This biomarker aids veterinarians in narrowing down the diagnostic process, guiding them towards the appropriate imaging or biopsy procedures. |

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