Feline HBP antibody and antigen (recombinant protein)

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Product information

Catalog No.	Description	US $ Price (per mg)
GMP-FEL-HBP-Ag01	Recombinant Feline HBP protein	3090
GMP-FEL-HBP-Ab01	Anti-Feline HBP mouse monoclonal antibody (mAb)	1953
GMP-FEL-HBP-Ab02	Anti-Feline HBP mouse monoclonal antibody (mAb)	1953
GMP-FEL-HBP-Ab03	Anti-Feline HBP human monoclonal antibody (mAb)	1953
GMP-FEL-HBP-Ab04	Anti-Feline HBP human monoclonal antibody (mAb)	1953

Size： 1mg | 10mg | 100mg

Product Description

Cat No. of Products	GMP-FEL-HBP-Ag01
Product Name	Recombinant Feline HBP protein
Target/Biomarker	Feline Heparin-binding protein (HBP)
Expression platform	E.coli
Isotypes	Recombinant Antigen
Bioactivity validation	Anti-Feline Heparin-binding protein antibodies binding, Immunogen in Sandwich Elisa, lateral-flow tests, and other immunoassays as control material in HBP level test of animal Cat/Feline with inflammation/autoimmune/ inflammatory disease.
Tag	His
Products description	Recombinant Feline HBP protein was expressed in E.coli - based prokaryotic cell expression system and is expressed with 6 HIS tag at the C-terminus.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-HBP-Ab01, GMP-FEL-HBP-Ab02
Product Name	Anti-Feline HBP mouse monoclonal antibody (mAb)
Target/Biomarker	Feline Heparin-binding protein (HBP)
Expression platform	CHO
Isotypes	Mouse IgG
Bioactivity validation	Recombinant Feline Heparin-binding protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HBP antibodies in HBP level test of animal Cat/Feline with inflammation/autoimmune/ inflammatory disease.
Tag	mFc
Products description	Anti-Feline HBP mouse monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HBP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Cat No. of Products	GMP-FEL-HBP-Ab03, GMP-FEL-HBP-Ab04
Product Name	Anti-Feline HBP human monoclonal antibody (mAb)
Target/Biomarker	Feline Heparin-binding protein (HBP)
Expression platform	CHO
Isotypes	Human IgG1
Bioactivity validation	Recombinant Feline Heparin-binding protein antigen binding, ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HBP antibodies in HBP level test of animal Cat/Feline with inflammation/autoimmune/ inflammatory disease.
Tag	hFc
Products description	Anti-Feline HBP human monoclonal antibody (mAb) is a monoclonal antibody produced by CHO technology. The antibody is ELISA validated as capture antibody and detection antibody. Pair recommendation with other anti-HBP antibodies.
Purity	Purity: ≥95% (SDS-PAGE)
Application	Paired antibody immunoassay validation in sandwich Elisa, ELISA, colloidal gold-based Lateral flow immunoassay (LFIA), CLIA, TINIA, POCT and other immunoassays
Formulation & Reconstitution	Lyophilized from GM's Protein Stability Buffer2 (PSB2,Confidential Ingredients) or PBS (pH7.4); For PSB2, reconstituted with 0.9% sodium chloride; For PBS, reconstituted with ddH2O.
Storage	Store at -20℃ to -80℃ under sterile conditions. Avoid repeated freeze-thaw cycles.

Reference

Validation Data

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Target/Biomarker information

Heparin-binding protein (HBP) in cats represents a remarkable example of the immune system's adaptability and multifaceted capabilities. Synthesized and secreted primarily by neutrophils, HBP plays a pivotal role in orchestrating immune responses and contributing to the body's defense mechanisms. Structurally, HBP exhibits a unique affinity for heparin, a glycosaminoglycan present in the extracellular matrix of tissues. This binding property allows HBP to interact with a range of molecules, facilitating its involvement in various immune processes. One of HBP's primary functions in cats is its role as a potent chemotactic agent. It acts as a signal, guiding immune cells, particularly neutrophils, to sites of infection or tissue damage. This chemotactic activity is crucial for the rapid and effective mobilization of immune defenses, enabling the containment and elimination of pathogens. Beyond its chemotactic role, HBP possesses antimicrobial properties. It targets bacterial membranes, disrupting their integrity and promoting bacterial cell lysis. This antimicrobial activity contributes to the innate immune response and complements the efforts of other immune components in fighting infections. Additionally, HBP plays a vital role in angiogenesis, the process of forming new blood vessels. This function is integral to tissue repair and regeneration. By modulating angiogenesis, HBP supports the delivery of oxygen and nutrients to injured tissues, facilitating their healing and recovery.

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